The role of macrophages phenotypes in the activation of resolution pathways within human granulosa cells

The role of macrophages phenotypes in the activation of resolution pathways within human granulosa cells

Abstract Background Inflammatory state within the ovaries can disrupt normal follicular dynamics, leading to reduced oocyte quality and infertility. How the production of inflammatory mediators generated by macrophages with different gene expression profile (M1 and M2) might activate inflammatory pa...

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Bibliographic Details
Main Authors: Thaise S. Martins, Bruno M. Fonseca, Irene Rebelo
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Reproductive Biology and Endocrinology
Subjects:
Inflammation
Infertility
Macrophage
Granulosa cells
Cyclooxygenase
Lipoxygenase
Online Access:https://doi.org/10.1186/s12958-022-00983-6

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