CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN
Cystic fibrosis is one of the severe childhood disorders with early manifestation of multiple organ involvement. The respiratory and digestive tracts are suffered the most, the prognosis of disease course depends on the degree of the impairment of these systems. The results of the analysis of cyst...
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"Paediatrician" Publishers LLC
2013-02-01
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Series: | Вопросы современной педиатрии |
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Online Access: | https://vsp.spr-journal.ru/jour/article/view/385 |
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author | T. G. Vasil’eva S. N. Shishatskaya A. N. Ni |
author_facet | T. G. Vasil’eva S. N. Shishatskaya A. N. Ni |
author_sort | T. G. Vasil’eva |
collection | DOAJ |
description | Cystic fibrosis is one of the severe childhood disorders with early manifestation of multiple organ involvement. The respiratory and digestive tracts are suffered the most, the prognosis of disease course depends on the degree of the impairment of these systems. The results of the analysis of cystic fibrosis prevalence in Primorsky Krai according to the neonatal immunoreactive trypsin screening in 102 251 newborn are shown in the article. The age, sex, clinical and severity structure of cystic fibrosis was studied in 71 children. The prevalence of 13 mutations of transmembrane regulator conductance gene in 41 patients was determined. Correlations between time of pulmonary complications manifestation, P. Aeruginosa infection development, chronic hypoxemia degree, malnutrition, genetic status and severity of the disease were found. |
first_indexed | 2024-03-12T04:22:29Z |
format | Article |
id | doaj.art-ef39dd2e234e482ea16fd2729931b6e9 |
institution | Directory Open Access Journal |
issn | 1682-5527 1682-5535 |
language | English |
last_indexed | 2024-03-12T04:22:29Z |
publishDate | 2013-02-01 |
publisher | "Paediatrician" Publishers LLC |
record_format | Article |
series | Вопросы современной педиатрии |
spelling | doaj.art-ef39dd2e234e482ea16fd2729931b6e92023-09-03T10:32:56Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352013-02-0112116216510.15690/vsp.v12i1.574385CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDRENT. G. Vasil’eva0S. N. Shishatskaya1A. N. Ni2Краевой клинический центр специализированных видов медицинской помощи», Владивосток; Дальневосточный филиал ФГБУ «НЦ ПЗСРЧ» СО РАМН, ВладивостокВладивостокский государственный медицинский университетВладивостокский государственный медицинский университетCystic fibrosis is one of the severe childhood disorders with early manifestation of multiple organ involvement. The respiratory and digestive tracts are suffered the most, the prognosis of disease course depends on the degree of the impairment of these systems. The results of the analysis of cystic fibrosis prevalence in Primorsky Krai according to the neonatal immunoreactive trypsin screening in 102 251 newborn are shown in the article. The age, sex, clinical and severity structure of cystic fibrosis was studied in 71 children. The prevalence of 13 mutations of transmembrane regulator conductance gene in 41 patients was determined. Correlations between time of pulmonary complications manifestation, P. Aeruginosa infection development, chronic hypoxemia degree, malnutrition, genetic status and severity of the disease were found.https://vsp.spr-journal.ru/jour/article/view/385муковисцидоздетиорганы дыханияпищеварения |
spellingShingle | T. G. Vasil’eva S. N. Shishatskaya A. N. Ni CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN Вопросы современной педиатрии муковисцидоз дети органы дыхания пищеварения |
title | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
title_full | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
title_fullStr | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
title_full_unstemmed | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
title_short | CERTAIN ASPECTS OF RESPIRATORY AND DIGESTIVE TRACT INVOLVEMENT IN CYSTIC FIBROSIS IN CHILDREN |
title_sort | certain aspects of respiratory and digestive tract involvement in cystic fibrosis in children |
topic | муковисцидоз дети органы дыхания пищеварения |
url | https://vsp.spr-journal.ru/jour/article/view/385 |
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