The Association between Vitamin D and Wheezing

Objective: To determine the association between vitamin D status and recurrent wheezing. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Paediatrics, Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Aug 2019 to Aug 2020. Methodolo...

Full description

Bibliographic Details
Main Authors: Murtaza Hussain, Qudratullah Malik, Qamar uz Zaman Khan, Junaid Bashir, Muhammad Abbas, Maryam Ijaz
Format: Article
Language:English
Published: Army Medical College Rawalpindi 2022-11-01
Series:Pakistan Armed Forces Medical Journal
Subjects:
Online Access:https://www.pafmj.org/index.php/PAFMJ/article/view/5175
_version_ 1811212204442124288
author Murtaza Hussain
Qudratullah Malik
Qamar uz Zaman Khan
Junaid Bashir
Muhammad Abbas
Maryam Ijaz
author_facet Murtaza Hussain
Qudratullah Malik
Qamar uz Zaman Khan
Junaid Bashir
Muhammad Abbas
Maryam Ijaz
author_sort Murtaza Hussain
collection DOAJ
description Objective: To determine the association between vitamin D status and recurrent wheezing. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Paediatrics, Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Aug 2019 to Aug 2020. Methodology: Sixty infants with recurrent wheezing and 60 healthy age-matched infants without acute or chronic illness were inducted into the study. 25 (OH) Vitamin D, immunoglobulin E (IgE) levels and eosinophil counts were measured. In addition, data were analyzed to find the association of vitamin D levels with recurrent wheezing. Results: In the Control-Group, the mean 25 (OH) vitamin D levels were 25.90±7.57 ng/ml and in the Recurrent Attack- Group was 13.90±4.63 ng/ml (p= 0.02). The mean IgE levels of the Control-Group were 22.80±2.67 IU/ml, and the Recurrent Attack-Group was 149.20±30.60 IU/ml (p=0.001). Eosinophil count in Recurrent Attack-Group was 150.40±23.11 cells/uL and 338.95±33.50 cells/uL in Control-Group respectively (p= 0.08) Conclusion: There is a strong association between low vitamin D levels and recurrent wheezing.
first_indexed 2024-04-12T05:25:14Z
format Article
id doaj.art-ef3feb761e36478c9191d8e979280070
institution Directory Open Access Journal
issn 0030-9648
2411-8842
language English
last_indexed 2024-04-12T05:25:14Z
publishDate 2022-11-01
publisher Army Medical College Rawalpindi
record_format Article
series Pakistan Armed Forces Medical Journal
spelling doaj.art-ef3feb761e36478c9191d8e9792800702022-12-22T03:46:20ZengArmy Medical College RawalpindiPakistan Armed Forces Medical Journal0030-96482411-88422022-11-0172510.51253/pafmj.v72i5.5175The Association between Vitamin D and WheezingMurtaza Hussain0Qudratullah Malik1Qamar uz Zaman Khan2Junaid Bashir3Muhammad Abbas4Maryam Ijaz5Pak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanPak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanCombined Military Hospital Kharian/National University of Medical Sciences (NUMS) PakistanPak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi PakistanPakistan Air Force Hospital, Islamabad PakistanPak Emirates Military Hospital/National University of Medical Sciences (NUMS) Rawalpindi Pakistan Objective: To determine the association between vitamin D status and recurrent wheezing. Study Design: Comparative cross-sectional study. Place and Duration of Study: Department of Paediatrics, Pak Emirates Military Hospital (PEMH), Rawalpindi Pakistan, from Aug 2019 to Aug 2020. Methodology: Sixty infants with recurrent wheezing and 60 healthy age-matched infants without acute or chronic illness were inducted into the study. 25 (OH) Vitamin D, immunoglobulin E (IgE) levels and eosinophil counts were measured. In addition, data were analyzed to find the association of vitamin D levels with recurrent wheezing. Results: In the Control-Group, the mean 25 (OH) vitamin D levels were 25.90±7.57 ng/ml and in the Recurrent Attack- Group was 13.90±4.63 ng/ml (p= 0.02). The mean IgE levels of the Control-Group were 22.80±2.67 IU/ml, and the Recurrent Attack-Group was 149.20±30.60 IU/ml (p=0.001). Eosinophil count in Recurrent Attack-Group was 150.40±23.11 cells/uL and 338.95±33.50 cells/uL in Control-Group respectively (p= 0.08) Conclusion: There is a strong association between low vitamin D levels and recurrent wheezing. https://www.pafmj.org/index.php/PAFMJ/article/view/5175Immunoglobulin EVitamin DWheeze
spellingShingle Murtaza Hussain
Qudratullah Malik
Qamar uz Zaman Khan
Junaid Bashir
Muhammad Abbas
Maryam Ijaz
The Association between Vitamin D and Wheezing
Pakistan Armed Forces Medical Journal
Immunoglobulin E
Vitamin D
Wheeze
title The Association between Vitamin D and Wheezing
title_full The Association between Vitamin D and Wheezing
title_fullStr The Association between Vitamin D and Wheezing
title_full_unstemmed The Association between Vitamin D and Wheezing
title_short The Association between Vitamin D and Wheezing
title_sort association between vitamin d and wheezing
topic Immunoglobulin E
Vitamin D
Wheeze
url https://www.pafmj.org/index.php/PAFMJ/article/view/5175
work_keys_str_mv AT murtazahussain theassociationbetweenvitamindandwheezing
AT qudratullahmalik theassociationbetweenvitamindandwheezing
AT qamaruzzamankhan theassociationbetweenvitamindandwheezing
AT junaidbashir theassociationbetweenvitamindandwheezing
AT muhammadabbas theassociationbetweenvitamindandwheezing
AT maryamijaz theassociationbetweenvitamindandwheezing
AT murtazahussain associationbetweenvitamindandwheezing
AT qudratullahmalik associationbetweenvitamindandwheezing
AT qamaruzzamankhan associationbetweenvitamindandwheezing
AT junaidbashir associationbetweenvitamindandwheezing
AT muhammadabbas associationbetweenvitamindandwheezing
AT maryamijaz associationbetweenvitamindandwheezing