Cadence discovery: study protocol for a dose-finding and mechanism of action clinical trial of sodium benzoate in people with treatment-refractory schizophrenia

Cadence discovery: study protocol for a dose-finding and mechanism of action clinical trial of sodium benzoate in people with treatment-refractory schizophrenia

Abstract Background Schizophrenia is a persistent psychotic disorder often accompanied by severe disability and premature mortality. New pharmacological treatments are urgently needed. Sodium benzoate, a common food preservative holds potential to be an effective, accessible treatment for schizophre...

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Bibliographic Details
Main Authors: Andrea Baker, Lachlan Clarke, Peter Donovan, Jacobus P. J. Ungerer, Gunter Hartel, George Bruxner, Luca Cocchi, Anne Gordon, Vikas Moudgil, Gail Robinson, Digant Roy, Ravinder Sohal, Emma Whittle, James G. Scott
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Trials
Subjects:
Schizophrenia
Adjunctive
Treatment refractory
Sodium benzoate
Intervention
RCT
Online Access:https://doi.org/10.1186/s13063-021-05890-6

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