Cancers in Australia in 2010 attributable to overweight and obesity
Abstract Objectives: To estimate the proportion and number of cancers occurring in Australia in 2010 attributable to overweight/obesity. Methods: We estimated the population attributable fraction (PAF) and number of cancers causally associated with overweight/obesity. We used standard formulae incor...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-10-01
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| Series: | Australian and New Zealand Journal of Public Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/1753-6405.12458 |
| _version_ | 1797728794656636928 |
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| author | Bradley J. Kendall Louise F. Wilson Catherine M. Olsen Penelope M. Webb Rachel E. Neale Christopher J. Bain David C. Whiteman |
| author_facet | Bradley J. Kendall Louise F. Wilson Catherine M. Olsen Penelope M. Webb Rachel E. Neale Christopher J. Bain David C. Whiteman |
| author_sort | Bradley J. Kendall |
| collection | DOAJ |
| description | Abstract Objectives: To estimate the proportion and number of cancers occurring in Australia in 2010 attributable to overweight/obesity. Methods: We estimated the population attributable fraction (PAF) and number of cancers causally associated with overweight/obesity. We used standard formulae incorporating Australian prevalence data for body mass index (BMI), relative risks associated with BMI and cancer. We also estimated the proportion change in cancer incidence (potential impact fraction [PIF]) that may have occurred assuming that the prevalence of overweight/obesity had remained at 1990 levels. Results: An estimated 3,917 cancer cases (3.4% of all cancers) diagnosed in 2010 were attributable to overweight/obesity, including 1,101 colon cancers, 971 female post‐menopausal breast cancers and 595 endometrial cancers (PAFs of 10%, 8% and 26%, respectively). Highest PAFs were observed for oesophageal adenocarcinoma (31%), endometrial cancer (26%) and kidney cancer (19%). If the prevalence of overweight/obesity in Australia had remained at levels prevailing in 1990, we estimate there would have been 820 fewer cancers diagnosed in 2010 (PIF 2%). Conclusions: Overweight/obesity causes a substantial number of cancers in Australia. Implications: Public health strategies to reduce the prevalence of overweight and obesity will reduce the incidence of cancer, particularly of the colon, breast and endometrium. |
| first_indexed | 2024-03-12T11:20:13Z |
| format | Article |
| id | doaj.art-ef44519ca0be4bbbb4af6b0e39f7c8cc |
| institution | Directory Open Access Journal |
| issn | 1326-0200 1753-6405 |
| language | English |
| last_indexed | 2024-03-12T11:20:13Z |
| publishDate | 2015-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Australian and New Zealand Journal of Public Health |
| spelling | doaj.art-ef44519ca0be4bbbb4af6b0e39f7c8cc2023-09-02T01:19:03ZengElsevierAustralian and New Zealand Journal of Public Health1326-02001753-64052015-10-0139545245710.1111/1753-6405.12458Cancers in Australia in 2010 attributable to overweight and obesityBradley J. Kendall0Louise F. Wilson1Catherine M. Olsen2Penelope M. Webb3Rachel E. Neale4Christopher J. Bain5David C. Whiteman6QIMR Berghofer Medical Research Institute QueenslandQIMR Berghofer Medical Research Institute QueenslandQIMR Berghofer Medical Research Institute QueenslandQIMR Berghofer Medical Research Institute QueenslandQIMR Berghofer Medical Research Institute QueenslandQIMR Berghofer Medical Research Institute QueenslandQIMR Berghofer Medical Research Institute QueenslandAbstract Objectives: To estimate the proportion and number of cancers occurring in Australia in 2010 attributable to overweight/obesity. Methods: We estimated the population attributable fraction (PAF) and number of cancers causally associated with overweight/obesity. We used standard formulae incorporating Australian prevalence data for body mass index (BMI), relative risks associated with BMI and cancer. We also estimated the proportion change in cancer incidence (potential impact fraction [PIF]) that may have occurred assuming that the prevalence of overweight/obesity had remained at 1990 levels. Results: An estimated 3,917 cancer cases (3.4% of all cancers) diagnosed in 2010 were attributable to overweight/obesity, including 1,101 colon cancers, 971 female post‐menopausal breast cancers and 595 endometrial cancers (PAFs of 10%, 8% and 26%, respectively). Highest PAFs were observed for oesophageal adenocarcinoma (31%), endometrial cancer (26%) and kidney cancer (19%). If the prevalence of overweight/obesity in Australia had remained at levels prevailing in 1990, we estimate there would have been 820 fewer cancers diagnosed in 2010 (PIF 2%). Conclusions: Overweight/obesity causes a substantial number of cancers in Australia. Implications: Public health strategies to reduce the prevalence of overweight and obesity will reduce the incidence of cancer, particularly of the colon, breast and endometrium.https://doi.org/10.1111/1753-6405.12458population attributable fractioncancerrisk factorobesitypotential impact fraction |
| spellingShingle | Bradley J. Kendall Louise F. Wilson Catherine M. Olsen Penelope M. Webb Rachel E. Neale Christopher J. Bain David C. Whiteman Cancers in Australia in 2010 attributable to overweight and obesity Australian and New Zealand Journal of Public Health population attributable fraction cancer risk factor obesity potential impact fraction |
| title | Cancers in Australia in 2010 attributable to overweight and obesity |
| title_full | Cancers in Australia in 2010 attributable to overweight and obesity |
| title_fullStr | Cancers in Australia in 2010 attributable to overweight and obesity |
| title_full_unstemmed | Cancers in Australia in 2010 attributable to overweight and obesity |
| title_short | Cancers in Australia in 2010 attributable to overweight and obesity |
| title_sort | cancers in australia in 2010 attributable to overweight and obesity |
| topic | population attributable fraction cancer risk factor obesity potential impact fraction |
| url | https://doi.org/10.1111/1753-6405.12458 |
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