Effects of long-term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidence
Background: Epidemiological evidence on the association of PM2.5 (particulate matter with aerodynamic diameter ≤ 2.5 μm) and its specific components with hypertension and blood pressure is limited. Methods: We applied information of participants from the World Health Organization's (WHO) Study...
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| Language: | English |
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Elsevier
2024-02-01
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| Series: | Environment International |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412024000503 |
| _version_ | 1797302577828724736 |
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| author | Li Fu Yanfei Guo Qijiong Zhu Zhiqing Chen Siwen Yu Jiahong Xu Weiling Tang Cuiling Wu Guanhao He Jianxiong Hu Fangfang Zeng Xiaomei Dong Pan Yang Ziqiang Lin Fan Wu Tao Liu Wenjun Ma |
| author_facet | Li Fu Yanfei Guo Qijiong Zhu Zhiqing Chen Siwen Yu Jiahong Xu Weiling Tang Cuiling Wu Guanhao He Jianxiong Hu Fangfang Zeng Xiaomei Dong Pan Yang Ziqiang Lin Fan Wu Tao Liu Wenjun Ma |
| author_sort | Li Fu |
| collection | DOAJ |
| description | Background: Epidemiological evidence on the association of PM2.5 (particulate matter with aerodynamic diameter ≤ 2.5 μm) and its specific components with hypertension and blood pressure is limited. Methods: We applied information of participants from the World Health Organization's (WHO) Study on Global Ageing and Adult Health (SAGE) to estimate the associations of long-term PM2.5 mass and its chemical components exposure with blood pressure (BP) and hypertension incidence in Chinese adults ≥ 50 years during 2007–2018. Generalized linear mixed model and Cox proportional hazard model were applied to investigate the effects of PM2.5 mass and its chemical components on the incidence of hypertension and BP, respectively. Results: Each interquartile range (IQR = 16.80 μg/m3) increase in the one-year average of PM2.5 mass concentration was associated with a 17 % increase in the risk of hypertension (HR = 1.17, 95 % CI: 1.10, 1.24), and the population attributable fraction (PAF) was 23.44 % (95 % CI: 14.69 %, 31.55 %). Each IQR μg/m3 increase in PM2.5 exposure was also related to increases of systolic blood pressure (SBP) by 2.54 mmHg (95 % CI:1.99, 3.10), and of diastolic blood pressure (DBP) by 1.36 mmHg (95 % CI: 1.04, 1.68). Additionally, the chemical components of SO42−, NO3−, NH4+, OM, and BC were also positively associated with an increased risk of hypertension incidence and elevated blood pressure. Conclusions: These results indicate that long-term exposure to PM2.5 mass and its specific components may be major drivers of escalation in hypertension diseases. |
| first_indexed | 2024-03-07T23:39:52Z |
| format | Article |
| id | doaj.art-ef4454f1ce7a4fa98c0b5b6d359ade95 |
| institution | Directory Open Access Journal |
| issn | 0160-4120 |
| language | English |
| last_indexed | 2024-03-07T23:39:52Z |
| publishDate | 2024-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj.art-ef4454f1ce7a4fa98c0b5b6d359ade952024-02-20T04:18:24ZengElsevierEnvironment International0160-41202024-02-01184108464Effects of long-term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidenceLi Fu0Yanfei Guo1Qijiong Zhu2Zhiqing Chen3Siwen Yu4Jiahong Xu5Weiling Tang6Cuiling Wu7Guanhao He8Jianxiong Hu9Fangfang Zeng10Xiaomei Dong11Pan Yang12Ziqiang Lin13Fan Wu14Tao Liu15Wenjun Ma16Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; Tianhe District Center for Disease Control and Prevention, Guangzhou 510655, ChinaShanghai Municipal Centre for Disease Control and Prevention, Shanghai 200336, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaDepartment of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaShanghai Medical College, Fudan University, Shanghai 200032, China; Corresponding authors at: Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China (T. Liu).Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, China; Corresponding authors at: Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China (T. Liu).Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China; China Greater Bay Area Research Center of Environmental Health, School of Medicine, Jinan University, Guangzhou 510632, ChinaBackground: Epidemiological evidence on the association of PM2.5 (particulate matter with aerodynamic diameter ≤ 2.5 μm) and its specific components with hypertension and blood pressure is limited. Methods: We applied information of participants from the World Health Organization's (WHO) Study on Global Ageing and Adult Health (SAGE) to estimate the associations of long-term PM2.5 mass and its chemical components exposure with blood pressure (BP) and hypertension incidence in Chinese adults ≥ 50 years during 2007–2018. Generalized linear mixed model and Cox proportional hazard model were applied to investigate the effects of PM2.5 mass and its chemical components on the incidence of hypertension and BP, respectively. Results: Each interquartile range (IQR = 16.80 μg/m3) increase in the one-year average of PM2.5 mass concentration was associated with a 17 % increase in the risk of hypertension (HR = 1.17, 95 % CI: 1.10, 1.24), and the population attributable fraction (PAF) was 23.44 % (95 % CI: 14.69 %, 31.55 %). Each IQR μg/m3 increase in PM2.5 exposure was also related to increases of systolic blood pressure (SBP) by 2.54 mmHg (95 % CI:1.99, 3.10), and of diastolic blood pressure (DBP) by 1.36 mmHg (95 % CI: 1.04, 1.68). Additionally, the chemical components of SO42−, NO3−, NH4+, OM, and BC were also positively associated with an increased risk of hypertension incidence and elevated blood pressure. Conclusions: These results indicate that long-term exposure to PM2.5 mass and its specific components may be major drivers of escalation in hypertension diseases.http://www.sciencedirect.com/science/article/pii/S0160412024000503PM2.5 componentsBPEffect modificationPopulation attributable fraction (PAF) |
| spellingShingle | Li Fu Yanfei Guo Qijiong Zhu Zhiqing Chen Siwen Yu Jiahong Xu Weiling Tang Cuiling Wu Guanhao He Jianxiong Hu Fangfang Zeng Xiaomei Dong Pan Yang Ziqiang Lin Fan Wu Tao Liu Wenjun Ma Effects of long-term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidence Environment International PM2.5 components BP Effect modification Population attributable fraction (PAF) |
| title | Effects of long-term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidence |
| title_full | Effects of long-term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidence |
| title_fullStr | Effects of long-term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidence |
| title_full_unstemmed | Effects of long-term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidence |
| title_short | Effects of long-term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidence |
| title_sort | effects of long term exposure to ambient fine particulate matter and its specific components on blood pressure and hypertension incidence |
| topic | PM2.5 components BP Effect modification Population attributable fraction (PAF) |
| url | http://www.sciencedirect.com/science/article/pii/S0160412024000503 |
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