Monitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activity
Heavy metals as pollutants in the working and living environment are a serious health and environmental problem because they are toxic, non-biodegradable, accumulate in living systems and have a long half-life in soil. Sources of lead contamination are combustion products in the chemical industr...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Association of Chemical Engineers of Serbia
2011-01-01
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| Series: | Hemijska Industrija |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0367-598X/2011/0367-598X1100027N.pdf |
| _version_ | 1819040290401419264 |
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| author | Nikolić Ružica S. Jovanović Jasmina M. Kocić Gordana M. Cvetković Tatjana P. Stojanović Svetlana R. Anđelković Tatjana D. Krstić Nenad S. |
| author_facet | Nikolić Ružica S. Jovanović Jasmina M. Kocić Gordana M. Cvetković Tatjana P. Stojanović Svetlana R. Anđelković Tatjana D. Krstić Nenad S. |
| author_sort | Nikolić Ružica S. |
| collection | DOAJ |
| description | Heavy metals as pollutants in the working and living environment are a serious health and environmental problem because they are toxic, non-biodegradable, accumulate in living systems and have a long half-life in soil. Sources of lead contamination are combustion products in the chemical industry and metallurgy, industrial waste water, landfills, traffic etc. Lead enters into the body via the food chain and drinking water. In the body lead is deposited in the liver, kidneys, brain and mineral tissues. Excretion of lead causes damage to the epithelial cells of certain organs. High level exposure to cadmium is usually the result of environmental pollution by human activities. Exposure to cadmium can lead to acute and chronic tissue damage of various organs, including liver and kidneys in humans and in animals. In this paper we analyzed the effects of lead and cadmium exposure, in working and living environment, on the model system of experimental animals, particularly the activity of certain liver enzymes, acid and alkaline DNase, and standard biochemical blood parameters. The study showed that lead and cadmium significantly affect the protein content, red blood cells, hemoglobin and hematocrit, and the activity of liver enzymes. This harmful effect of this toxic metal can be reduced by the supplements. |
| first_indexed | 2024-12-21T09:06:45Z |
| format | Article |
| id | doaj.art-ef460a78367846c897fb1257d14fb064 |
| institution | Directory Open Access Journal |
| issn | 0367-598X |
| language | English |
| last_indexed | 2024-12-21T09:06:45Z |
| publishDate | 2011-01-01 |
| publisher | Association of Chemical Engineers of Serbia |
| record_format | Article |
| series | Hemijska Industrija |
| spelling | doaj.art-ef460a78367846c897fb1257d14fb0642022-12-21T19:09:20ZengAssociation of Chemical Engineers of SerbiaHemijska Industrija0367-598X2011-01-0165440340910.2298/HEMIND110308027NMonitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activityNikolić Ružica S.Jovanović Jasmina M.Kocić Gordana M.Cvetković Tatjana P.Stojanović Svetlana R.Anđelković Tatjana D.Krstić Nenad S.Heavy metals as pollutants in the working and living environment are a serious health and environmental problem because they are toxic, non-biodegradable, accumulate in living systems and have a long half-life in soil. Sources of lead contamination are combustion products in the chemical industry and metallurgy, industrial waste water, landfills, traffic etc. Lead enters into the body via the food chain and drinking water. In the body lead is deposited in the liver, kidneys, brain and mineral tissues. Excretion of lead causes damage to the epithelial cells of certain organs. High level exposure to cadmium is usually the result of environmental pollution by human activities. Exposure to cadmium can lead to acute and chronic tissue damage of various organs, including liver and kidneys in humans and in animals. In this paper we analyzed the effects of lead and cadmium exposure, in working and living environment, on the model system of experimental animals, particularly the activity of certain liver enzymes, acid and alkaline DNase, and standard biochemical blood parameters. The study showed that lead and cadmium significantly affect the protein content, red blood cells, hemoglobin and hematocrit, and the activity of liver enzymes. This harmful effect of this toxic metal can be reduced by the supplements.http://www.doiserbia.nb.rs/img/doi/0367-598X/2011/0367-598X1100027N.pdfLeadcadmiumtoxicityhematological parametersliver enzymes |
| spellingShingle | Nikolić Ružica S. Jovanović Jasmina M. Kocić Gordana M. Cvetković Tatjana P. Stojanović Svetlana R. Anđelković Tatjana D. Krstić Nenad S. Monitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activity Hemijska Industrija Lead cadmium toxicity hematological parameters liver enzymes |
| title | Monitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activity |
| title_full | Monitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activity |
| title_fullStr | Monitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activity |
| title_full_unstemmed | Monitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activity |
| title_short | Monitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activity |
| title_sort | monitoring the effects of exposure to lead and cadmium in working and living environment through standard biochemical blood parameters and liver endonucleases activity |
| topic | Lead cadmium toxicity hematological parameters liver enzymes |
| url | http://www.doiserbia.nb.rs/img/doi/0367-598X/2011/0367-598X1100027N.pdf |
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