Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyes
Background: Glaucoma is an optic neuropathy which causes irreversible vision loss. Standard perimetry, which is essential for glaucoma diagnosis, can only detect glaucomatous visual filed loss when considerable structural damage has occurred. Contrast sensitivity is one of the visual function tests...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2023-10-01
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| Series: | Therapeutic Advances in Ophthalmology |
| Online Access: | https://doi.org/10.1177/25158414231208284 |
| _version_ | 1827778488465096704 |
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| author | Emmanuel Kwasi Abu Carl Halladay Abraham Albert Kofi Dadzie Enyam Amewuho Morny Michael Ntodie Stephen Ocansey Samuel Abokyi Andrew Owusu-Ansah Naa Adjeley Addo Michael Williams Asantewaa Aboagye-McCarthy Godfred Sakyi-Badu Paa Kwesi Fynn Hope Peter Osei-Wusu Adueming |
| author_facet | Emmanuel Kwasi Abu Carl Halladay Abraham Albert Kofi Dadzie Enyam Amewuho Morny Michael Ntodie Stephen Ocansey Samuel Abokyi Andrew Owusu-Ansah Naa Adjeley Addo Michael Williams Asantewaa Aboagye-McCarthy Godfred Sakyi-Badu Paa Kwesi Fynn Hope Peter Osei-Wusu Adueming |
| author_sort | Emmanuel Kwasi Abu |
| collection | DOAJ |
| description | Background: Glaucoma is an optic neuropathy which causes irreversible vision loss. Standard perimetry, which is essential for glaucoma diagnosis, can only detect glaucomatous visual filed loss when considerable structural damage has occurred. Contrast sensitivity is one of the visual function tests that is reduced in eyes with glaucoma. It is known to be affected in pre-perimetric stages of glaucoma. Objective: The objective of this study was to investigate the discriminating ability of central contrast sensitivity perimetry in eyes with and without glaucoma. Design: The study employed a cross-sectional study design. Methods: The study participants were made of two groups; eyes diagnosed with glaucoma by an ophthalmologist based on visual field test and optical coherence tomography (OCT) and age- and sex-matched controls who were declared free from glaucoma. Static contrast sensitivity (CS) was measured in the central 10° of visual field using a custom psychophysical test. Results: There were 45 eyes with glaucoma and 45 age- and sex-matched controls in this study. The static CS in the glaucoma group was significantly reduced in 9 out of the 13 tested locations in the central 10° of the visual field. The mean static CS at 5°, 10°, superior hemifield and inferior hemifield were all significantly reduced in the glaucoma patients compared to the controls. Conclusion: Static CS measurement is a sensitive approach that can be utilized to aid in the detection of glaucoma. The use of static CS can be adopted in the development of a cost-effective yet sensitive screening tool for the detection of glaucoma. |
| first_indexed | 2024-03-11T14:34:57Z |
| format | Article |
| id | doaj.art-ef46a1cd67c8464797383a913458ddcb |
| institution | Directory Open Access Journal |
| issn | 2515-8414 |
| language | English |
| last_indexed | 2024-03-11T14:34:57Z |
| publishDate | 2023-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Ophthalmology |
| spelling | doaj.art-ef46a1cd67c8464797383a913458ddcb2023-10-31T05:33:39ZengSAGE PublishingTherapeutic Advances in Ophthalmology2515-84142023-10-011510.1177/25158414231208284Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyesEmmanuel Kwasi AbuCarl Halladay AbrahamAlbert Kofi DadzieEnyam Amewuho MornyMichael NtodieStephen OcanseySamuel AbokyiAndrew Owusu-AnsahNaa Adjeley AddoMichael WilliamsAsantewaa Aboagye-McCarthyGodfred Sakyi-BaduPaa Kwesi Fynn HopePeter Osei-Wusu AduemingBackground: Glaucoma is an optic neuropathy which causes irreversible vision loss. Standard perimetry, which is essential for glaucoma diagnosis, can only detect glaucomatous visual filed loss when considerable structural damage has occurred. Contrast sensitivity is one of the visual function tests that is reduced in eyes with glaucoma. It is known to be affected in pre-perimetric stages of glaucoma. Objective: The objective of this study was to investigate the discriminating ability of central contrast sensitivity perimetry in eyes with and without glaucoma. Design: The study employed a cross-sectional study design. Methods: The study participants were made of two groups; eyes diagnosed with glaucoma by an ophthalmologist based on visual field test and optical coherence tomography (OCT) and age- and sex-matched controls who were declared free from glaucoma. Static contrast sensitivity (CS) was measured in the central 10° of visual field using a custom psychophysical test. Results: There were 45 eyes with glaucoma and 45 age- and sex-matched controls in this study. The static CS in the glaucoma group was significantly reduced in 9 out of the 13 tested locations in the central 10° of the visual field. The mean static CS at 5°, 10°, superior hemifield and inferior hemifield were all significantly reduced in the glaucoma patients compared to the controls. Conclusion: Static CS measurement is a sensitive approach that can be utilized to aid in the detection of glaucoma. The use of static CS can be adopted in the development of a cost-effective yet sensitive screening tool for the detection of glaucoma.https://doi.org/10.1177/25158414231208284 |
| spellingShingle | Emmanuel Kwasi Abu Carl Halladay Abraham Albert Kofi Dadzie Enyam Amewuho Morny Michael Ntodie Stephen Ocansey Samuel Abokyi Andrew Owusu-Ansah Naa Adjeley Addo Michael Williams Asantewaa Aboagye-McCarthy Godfred Sakyi-Badu Paa Kwesi Fynn Hope Peter Osei-Wusu Adueming Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyes Therapeutic Advances in Ophthalmology |
| title | Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyes |
| title_full | Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyes |
| title_fullStr | Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyes |
| title_full_unstemmed | Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyes |
| title_short | Central contrast sensitivity perimetry discriminates between glaucomatous and non-glaucomatous eyes |
| title_sort | central contrast sensitivity perimetry discriminates between glaucomatous and non glaucomatous eyes |
| url | https://doi.org/10.1177/25158414231208284 |
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