Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT

Silver-impregnated, antibiotic-impregnated or non-impregnated ventriculoperitoneal shunts to prevent shunt infection: the BASICS three-arm RCT

Background: Insertion of a ventriculoperitoneal shunt to treat hydrocephalus is one of the most common neurosurgical procedures worldwide. Shunt infection affects up to 15% of patients, resulting in long hospital stays, multiple surgeries and reduced cognition and quality of life. Objectives: The ai...

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Main Authors: Conor L Mallucci, Michael D Jenkinson, Elizabeth J Conroy, John C Hartley, Michaela Brown, Tracy Moitt, Joanne Dalton, Tom Kearns, Michael J Griffiths, Giovanna Culeddu, Tom Solomon, Dyfrig Hughes, Carrol Gamble, the BASICS study collaborators
Format: Article
Language:English
Published: NIHR Journals Library 2020-03-01
Series:Health Technology Assessment
Subjects:
ventriculoperitoneal shunt
infection
clinical trial
antibiotic
silver
standard
hydrocephalus
rifampicin
clindamycin
Online Access:https://doi.org/10.3310/hta24170

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