Dietary Iron Overload and <i>Hfe<sup>−/−</sup></i> Related Hemochromatosis Alter Hepatic Mitochondrial Function

Dietary Iron Overload and <i>Hfe<sup>−/−</sup></i> Related Hemochromatosis Alter Hepatic Mitochondrial Function

Iron is an essential co-factor for many cellular metabolic processes, and mitochondria are main sites of utilization. Iron accumulation promotes production of reactive oxygen species (ROS) via the catalytic activity of iron species. Herein, we investigated the consequences of dietary and genetic iro...

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書目詳細資料
Main Authors: Christine Fischer, Chiara Volani, Timea Komlódi, Markus Seifert, Egon Demetz, Lara Valente de Souza, Kristina Auer, Verena Petzer, Laura von Raffay, Patrizia Moser, Erich Gnaiger, Guenter Weiss
格式: Article
語言:English
出版: MDPI AG 2021-11-01
叢編:Antioxidants
主題:
hemochromatosis
iron overload
reactive oxygen species
mitochondria
mitochondrial respiration
liver
在線閱讀:https://www.mdpi.com/2076-3921/10/11/1818

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https://www.mdpi.com/2076-3921/10/11/1818

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