Physico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration.
Sugar-based biosurfactants such as xylose-derived bolaforms have interesting properties, for example high biocompatibility and biodegradability which make them potential useful molecules in the pharmaceutical and cosmetic fields. Until now, no detailed analyses of the physico-chemical properties of...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
EDP Sciences
2013-08-01
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| Series: | MATEC Web of Conferences |
| Online Access: | http://dx.doi.org/10.1051/matecconf/20130404003 |
| _version_ | 1818865816489164800 |
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| author | Nasir M. N. Legrand V. Gatard S. Bouquillon S. Nott K. Lins L. Deleu M. |
| author_facet | Nasir M. N. Legrand V. Gatard S. Bouquillon S. Nott K. Lins L. Deleu M. |
| author_sort | Nasir M. N. |
| collection | DOAJ |
| description | Sugar-based biosurfactants such as xylose-derived bolaforms have interesting properties, for example high biocompatibility and biodegradability which make them potential useful molecules in the pharmaceutical and cosmetic fields. Until now, no detailed analyses of the physico-chemical properties of these compounds have been undertaken. Two symmetrical D-xylose-based bolaforms were chemically synthesized where the two xylose heads are linked via an acetal link to a hydrocarbon chain containing 18 carbon atoms and an unsaturation. The two bolaforms differ only by their anomeric configuration: αα or ββ. The αα bolaform exhibits interfacial properties at the air-water interface which is not the case for the ββ. FTIR spectroscopy showed that the interactions between the αα bolaform and POPC, a model phospholipid, involve the carbonyl groups of the phospholipid. . |
| first_indexed | 2024-12-19T10:53:34Z |
| format | Article |
| id | doaj.art-ef4d270400a94022bdc6090c4029f3ad |
| institution | Directory Open Access Journal |
| issn | 2261-236X |
| language | English |
| last_indexed | 2024-12-19T10:53:34Z |
| publishDate | 2013-08-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | MATEC Web of Conferences |
| spelling | doaj.art-ef4d270400a94022bdc6090c4029f3ad2022-12-21T20:24:54ZengEDP SciencesMATEC Web of Conferences2261-236X2013-08-0140400310.1051/matecconf/20130404003Physico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration.Nasir M. N.Legrand V.Gatard S.Bouquillon S.Nott K.Lins L.Deleu M.Sugar-based biosurfactants such as xylose-derived bolaforms have interesting properties, for example high biocompatibility and biodegradability which make them potential useful molecules in the pharmaceutical and cosmetic fields. Until now, no detailed analyses of the physico-chemical properties of these compounds have been undertaken. Two symmetrical D-xylose-based bolaforms were chemically synthesized where the two xylose heads are linked via an acetal link to a hydrocarbon chain containing 18 carbon atoms and an unsaturation. The two bolaforms differ only by their anomeric configuration: αα or ββ. The αα bolaform exhibits interfacial properties at the air-water interface which is not the case for the ββ. FTIR spectroscopy showed that the interactions between the αα bolaform and POPC, a model phospholipid, involve the carbonyl groups of the phospholipid. .http://dx.doi.org/10.1051/matecconf/20130404003 |
| spellingShingle | Nasir M. N. Legrand V. Gatard S. Bouquillon S. Nott K. Lins L. Deleu M. Physico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration. MATEC Web of Conferences |
| title | Physico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration. |
| title_full | Physico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration. |
| title_fullStr | Physico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration. |
| title_full_unstemmed | Physico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration. |
| title_short | Physico-chemical and membrane-interacting properties of D-xylose-based bolaforms. Influence of the anomeric configuration. |
| title_sort | physico chemical and membrane interacting properties of d xylose based bolaforms influence of the anomeric configuration |
| url | http://dx.doi.org/10.1051/matecconf/20130404003 |
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