Selected hematological parameters and oxidative stress in red blood cells (RBCs) after accidental cases of nitrate toxicity in the goat fed cabbage
ABSTRACTNitrate poisoning due to the consumption of cabbages was diagnosed in a small goat flock, in Qena city, Egypt. The methylene blue 1% antidote (1 mg/kg BW) was given intravenously to the poisoned goats. Nitrate poisoning was confirmed in blood plasma, saliva, urine, and cabbage dry matter sam...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Journal of Applied Animal Research |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/09712119.2023.2194360 |
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| author | Atef M. Khalil Ibrahim F. Rehan František Zigo Šimon Halás Zuzana Farkašová Hassan M. Diab |
| author_facet | Atef M. Khalil Ibrahim F. Rehan František Zigo Šimon Halás Zuzana Farkašová Hassan M. Diab |
| author_sort | Atef M. Khalil |
| collection | DOAJ |
| description | ABSTRACTNitrate poisoning due to the consumption of cabbages was diagnosed in a small goat flock, in Qena city, Egypt. The methylene blue 1% antidote (1 mg/kg BW) was given intravenously to the poisoned goats. Nitrate poisoning was confirmed in blood plasma, saliva, urine, and cabbage dry matter samples. The dark brown blood and methemoglobin fraction were 47.25 ± 0.58%. Green cabbage containing 7.1% nitrate on dried materials was fed to the goats. The nitrate concentration in the saliva was (59.50 ± 4.67), compared to the healthy goats reared in the same area and tested positive in the plasma and urine of intoxicated goats. Intoxication induced a significant decline in the Red Blood Cells count, hemoglobin concentration, and HCT % (P < 0.001), while the WBC count (P < 0.001), neutrophils (P < 0.001), and monocyte percentage were elevated (P < 0.002) in intoxicated goats, while the lymphocyte % (P < 0.01) significantly decreased when compared to the control. For the oxidative stress in the red blood cells, nitrate toxicity caused a significant elevation in the concentration of Malondialdehyde, (P < 0.001) while Superoxide Dismutase, Glutathione, and Glutathione S-Transferase levels were significantly reduced (P < 0.001) compared to the control. In this current report, the ingestion of goat to cabbage containing a high level of nitrate exhibited nitrate-nitrite intoxication. |
| first_indexed | 2024-03-09T14:09:19Z |
| format | Article |
| id | doaj.art-ef4d556896cb4405adb9857c0f18195f |
| institution | Directory Open Access Journal |
| issn | 0971-2119 0974-1844 |
| language | English |
| last_indexed | 2024-03-09T14:09:19Z |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Applied Animal Research |
| spelling | doaj.art-ef4d556896cb4405adb9857c0f18195f2023-11-29T18:00:51ZengTaylor & Francis GroupJournal of Applied Animal Research0971-21190974-18442023-12-0151130030710.1080/09712119.2023.2194360Selected hematological parameters and oxidative stress in red blood cells (RBCs) after accidental cases of nitrate toxicity in the goat fed cabbageAtef M. Khalil0Ibrahim F. Rehan1František Zigo2Šimon Halás3Zuzana Farkašová4Hassan M. Diab5Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, South Valley University, Qena, EgyptDepartment of Husbandry and Development of Animal Wealth, Faculty of Veterinary Medicine, Menoufia University, Menoufia, EgyptDepartment of Animal Nutrition and Husbandry, University of Veterinary Medicine and Pharmacy, SlovakiaDepartment of Animal Nutrition and Husbandry, University of Veterinary Medicine and Pharmacy, SlovakiaDepartment of Animal Nutrition and Husbandry, University of Veterinary Medicine and Pharmacy, SlovakiaDepartment of Animal and Poultry Health and Environment, Faculty of Veterinary Medicine, South Valley University, Qena, EgyptABSTRACTNitrate poisoning due to the consumption of cabbages was diagnosed in a small goat flock, in Qena city, Egypt. The methylene blue 1% antidote (1 mg/kg BW) was given intravenously to the poisoned goats. Nitrate poisoning was confirmed in blood plasma, saliva, urine, and cabbage dry matter samples. The dark brown blood and methemoglobin fraction were 47.25 ± 0.58%. Green cabbage containing 7.1% nitrate on dried materials was fed to the goats. The nitrate concentration in the saliva was (59.50 ± 4.67), compared to the healthy goats reared in the same area and tested positive in the plasma and urine of intoxicated goats. Intoxication induced a significant decline in the Red Blood Cells count, hemoglobin concentration, and HCT % (P < 0.001), while the WBC count (P < 0.001), neutrophils (P < 0.001), and monocyte percentage were elevated (P < 0.002) in intoxicated goats, while the lymphocyte % (P < 0.01) significantly decreased when compared to the control. For the oxidative stress in the red blood cells, nitrate toxicity caused a significant elevation in the concentration of Malondialdehyde, (P < 0.001) while Superoxide Dismutase, Glutathione, and Glutathione S-Transferase levels were significantly reduced (P < 0.001) compared to the control. In this current report, the ingestion of goat to cabbage containing a high level of nitrate exhibited nitrate-nitrite intoxication.https://www.tandfonline.com/doi/10.1080/09712119.2023.2194360Nitrate poisoningcabbageclinical signshematological analyzesoxidative stress |
| spellingShingle | Atef M. Khalil Ibrahim F. Rehan František Zigo Šimon Halás Zuzana Farkašová Hassan M. Diab Selected hematological parameters and oxidative stress in red blood cells (RBCs) after accidental cases of nitrate toxicity in the goat fed cabbage Journal of Applied Animal Research Nitrate poisoning cabbage clinical signs hematological analyzes oxidative stress |
| title | Selected hematological parameters and oxidative stress in red blood cells (RBCs) after accidental cases of nitrate toxicity in the goat fed cabbage |
| title_full | Selected hematological parameters and oxidative stress in red blood cells (RBCs) after accidental cases of nitrate toxicity in the goat fed cabbage |
| title_fullStr | Selected hematological parameters and oxidative stress in red blood cells (RBCs) after accidental cases of nitrate toxicity in the goat fed cabbage |
| title_full_unstemmed | Selected hematological parameters and oxidative stress in red blood cells (RBCs) after accidental cases of nitrate toxicity in the goat fed cabbage |
| title_short | Selected hematological parameters and oxidative stress in red blood cells (RBCs) after accidental cases of nitrate toxicity in the goat fed cabbage |
| title_sort | selected hematological parameters and oxidative stress in red blood cells rbcs after accidental cases of nitrate toxicity in the goat fed cabbage |
| topic | Nitrate poisoning cabbage clinical signs hematological analyzes oxidative stress |
| url | https://www.tandfonline.com/doi/10.1080/09712119.2023.2194360 |
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