Iron Dysregulation in Alzheimer’s Disease: LA-ICP-MS Bioimaging of the Distribution of Iron and Ferroportin in the CA1 Region of the Human Hippocampus

Iron Dysregulation in Alzheimer’s Disease: LA-ICP-MS Bioimaging of the Distribution of Iron and Ferroportin in the CA1 Region of the Human Hippocampus

Alzheimer’s disease (AD) is a prevalent neurodegenerative disorder characterized by cognitive decline and neuropathological hallmarks, including β-amyloid (Aβ) plaques, Tau tangles, synaptic dysfunction and neurodegeneration. Emerging evidence suggests that abnormal iron (Fe) metabolism plays a role...

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Bibliographic Details
Main Authors: Susana Junceda, María Cruz-Alonso, Beatriz Fernandez, Rosario Pereiro, Eva Martínez-Pinilla, Ana Navarro
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Biomolecules
Subjects:
Alzheimer’s disease
iron transport proteins
ferroportin
iron homeostasis
β-amyloid
Tau
Online Access:https://www.mdpi.com/2218-273X/14/3/295

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