Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains
Abstract Introduction Port-wine stains (PWS) are congenital capillary abnormalities caused by immature, venule-like vasculature that progressively dilates due to poor endothelial cell differentiation. PWS affects between 0.3% and 0.9% of newborns, with 90% of cases occurring on the face. Individuals...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Adis, Springer Healthcare
2023-09-01
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| Series: | Dermatology and Therapy |
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| Online Access: | https://doi.org/10.1007/s13555-023-01011-0 |
| _version_ | 1797669608387248128 |
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| author | Tatre Jantarakolica Rungsima Wanitphakdeedecha Chadakan Yan Yuri Yogya Woraphong Manuskiatti Tatchalerm Sudhipongpracha |
| author_facet | Tatre Jantarakolica Rungsima Wanitphakdeedecha Chadakan Yan Yuri Yogya Woraphong Manuskiatti Tatchalerm Sudhipongpracha |
| author_sort | Tatre Jantarakolica |
| collection | DOAJ |
| description | Abstract Introduction Port-wine stains (PWS) are congenital capillary abnormalities caused by immature, venule-like vasculature that progressively dilates due to poor endothelial cell differentiation. PWS affects between 0.3% and 0.9% of newborns, with 90% of cases occurring on the face. Individuals with facial PWS and their parents had a significant negative impairment on their quality of life (QoL) and also suffered from psychological disabilities. Methods This was a cross-sectional questionnaire-based survey study in Thailand from July 2021 to April 2022. The questionnaires included demographic data, subjective evaluation (SE), and the Dermatology Life Quality Index (DLQI). The questionnaire was performed with a full scale and adjusted scale of validity and reliability test of DLQI using factor analysis and Cronbach’s alpha. The study outcome was a subjective evaluation and DLQI in patients who received pulsed dye laser (PDL) treatment. Results Of the 54 patients, 35.2% (19) are male, and 64.8% (35) are female. Regarding age groups, 64.8% (35) are below 5 years old, and 35.2% (19) are older than 5 years. SE results showed that males evaluated an improvement of the facial PWS lesion significantly better than females (P < 0.05). The older age group graded the percentage of improvement better than the younger age group (P < 0.01). The result of the DLQI showed no difference in DLQI between gender. Older age result resulted in a significantly different DLQI compared with younger age (P < 0.01). Parent-reported DLQI improvement was less than self-reported DLQI improvement in patients with PWS treated with PDL (P < 0.05). Concerning the instrument of the study, the validity and reliability analysis of the DLQI questionnaire using factor analysis and Cronbach’s alpha have been performed. The adjusted scale with the 5-item DLQI questionnaire is more appropriate in terms validity and reliability. Conclusion This study demonstrates that facial PWS reduces the QoL as measured by DLQI. We discovered that the QoL of patients and parents with PWS was significantly impaired. The main influencing factors were older age, the improved perception between gender, and PDL treatments. In addition, we found only five questions that are reliable for PWS. The adjusted five-item DLQI questionnaires are more appropriate regarding validity and reliability. Trial Registration Number TCTR20230210001, COA no. si 1059/2020. |
| first_indexed | 2024-03-11T20:46:55Z |
| format | Article |
| id | doaj.art-ef571faccd8640fbaaea0f408e0faa16 |
| institution | Directory Open Access Journal |
| issn | 2193-8210 2190-9172 |
| language | English |
| last_indexed | 2024-03-11T20:46:55Z |
| publishDate | 2023-09-01 |
| publisher | Adis, Springer Healthcare |
| record_format | Article |
| series | Dermatology and Therapy |
| spelling | doaj.art-ef571faccd8640fbaaea0f408e0faa162023-10-01T11:06:33ZengAdis, Springer HealthcareDermatology and Therapy2193-82102190-91722023-09-0113102375238610.1007/s13555-023-01011-0Dermatology Life Quality Index in Thai Patients with Facial Port-Wine StainsTatre Jantarakolica0Rungsima Wanitphakdeedecha1Chadakan Yan2Yuri Yogya3Woraphong Manuskiatti4Tatchalerm Sudhipongpracha5Faculty of Economics, Thammasat UniversityDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol UniversityCollege of Interdisciplinary Studies, Thammasat UniversityAbstract Introduction Port-wine stains (PWS) are congenital capillary abnormalities caused by immature, venule-like vasculature that progressively dilates due to poor endothelial cell differentiation. PWS affects between 0.3% and 0.9% of newborns, with 90% of cases occurring on the face. Individuals with facial PWS and their parents had a significant negative impairment on their quality of life (QoL) and also suffered from psychological disabilities. Methods This was a cross-sectional questionnaire-based survey study in Thailand from July 2021 to April 2022. The questionnaires included demographic data, subjective evaluation (SE), and the Dermatology Life Quality Index (DLQI). The questionnaire was performed with a full scale and adjusted scale of validity and reliability test of DLQI using factor analysis and Cronbach’s alpha. The study outcome was a subjective evaluation and DLQI in patients who received pulsed dye laser (PDL) treatment. Results Of the 54 patients, 35.2% (19) are male, and 64.8% (35) are female. Regarding age groups, 64.8% (35) are below 5 years old, and 35.2% (19) are older than 5 years. SE results showed that males evaluated an improvement of the facial PWS lesion significantly better than females (P < 0.05). The older age group graded the percentage of improvement better than the younger age group (P < 0.01). The result of the DLQI showed no difference in DLQI between gender. Older age result resulted in a significantly different DLQI compared with younger age (P < 0.01). Parent-reported DLQI improvement was less than self-reported DLQI improvement in patients with PWS treated with PDL (P < 0.05). Concerning the instrument of the study, the validity and reliability analysis of the DLQI questionnaire using factor analysis and Cronbach’s alpha have been performed. The adjusted scale with the 5-item DLQI questionnaire is more appropriate in terms validity and reliability. Conclusion This study demonstrates that facial PWS reduces the QoL as measured by DLQI. We discovered that the QoL of patients and parents with PWS was significantly impaired. The main influencing factors were older age, the improved perception between gender, and PDL treatments. In addition, we found only five questions that are reliable for PWS. The adjusted five-item DLQI questionnaires are more appropriate regarding validity and reliability. Trial Registration Number TCTR20230210001, COA no. si 1059/2020.https://doi.org/10.1007/s13555-023-01011-0Port-wine stainDLQISubjective evaluationQuality of life |
| spellingShingle | Tatre Jantarakolica Rungsima Wanitphakdeedecha Chadakan Yan Yuri Yogya Woraphong Manuskiatti Tatchalerm Sudhipongpracha Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains Dermatology and Therapy Port-wine stain DLQI Subjective evaluation Quality of life |
| title | Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains |
| title_full | Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains |
| title_fullStr | Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains |
| title_full_unstemmed | Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains |
| title_short | Dermatology Life Quality Index in Thai Patients with Facial Port-Wine Stains |
| title_sort | dermatology life quality index in thai patients with facial port wine stains |
| topic | Port-wine stain DLQI Subjective evaluation Quality of life |
| url | https://doi.org/10.1007/s13555-023-01011-0 |
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