Analisis Profil Bobot Badan Tikus dan Gejala Toksis Pada Pemberian Ekstrak Etanol Daun Parang Romang (Boehmeria virgata) Terhadap Tikus Putih (Rattus novergicus)
Traditional medicine is part of the Indonesian cultural heritage which has been used for generations and for centuries, but in general its safety has not been supported by adequate research. One of them is a parangromang which is empirically used by Makassar tribal healers as an antitumor. This stud...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Universitas Tadulako
2020-03-01
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| Series: | Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) |
| Subjects: | |
| Online Access: | https://bestjournal.untad.ac.id/index.php/Galenika/article/view/13928 |
| _version_ | 1819161623127916544 |
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| author | Magfirah lukman Vidya Christin |
| author_facet | Magfirah lukman Vidya Christin |
| author_sort | Magfirah lukman |
| collection | DOAJ |
| description | Traditional medicine is part of the Indonesian cultural heritage which has been used for generations and for centuries, but in general its safety has not been supported by adequate research. One of them is a parangromang which is empirically used by Makassar tribal healers as an antitumor. This study aims to determine theprofile Of body weight and toxic symptoms after 24 hours to 14 days including skin
and fur changes, tremors and seizures, comaof rats in the administration of ethanol extract parang romang. White rats were divided randomly into 4 groups: group one was given 0.5% NaCMC, groups of two, three and four were given extract at a dose of 175 mg / KgBB, 550 mg / KgBB and 1750 mg / KgBB for 14 days, the body
weights of rats on days 0, 7 and 14 days and toxic symptoms after 24 hours to 14 days.The results showed ethanol extract of parang romang leaves 550 mg / KgBB had an effect on increasing body weight of rats and there were no changes in skin and fur, spasms, tremor, coma and death. It can be concluded that the ethanol extract of parang romang leaves has a significant effect on increasing the weight profile of male white rats and there are no toxic symptoms. |
| first_indexed | 2024-12-22T17:15:17Z |
| format | Article |
| id | doaj.art-ef59f8a678cd4e41bc3afe5e7f01def0 |
| institution | Directory Open Access Journal |
| issn | 2442-7284 2442-8744 |
| language | English |
| last_indexed | 2024-12-22T17:15:17Z |
| publishDate | 2020-03-01 |
| publisher | Universitas Tadulako |
| record_format | Article |
| series | Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) |
| spelling | doaj.art-ef59f8a678cd4e41bc3afe5e7f01def02022-12-21T18:18:59ZengUniversitas TadulakoJurnal Farmasi Galenika (Galenika Journal of Pharmacy)2442-72842442-87442020-03-01611610.22487/j24428744.2020.v6.i1.1392813928Analisis Profil Bobot Badan Tikus dan Gejala Toksis Pada Pemberian Ekstrak Etanol Daun Parang Romang (Boehmeria virgata) Terhadap Tikus Putih (Rattus novergicus)Magfirah lukman0Vidya Christin1Sekolah Tinggi Ilmu Farmasi Pelita Mas (STIFA-PM) PaluSekolah Tinggi Ilmu Farmasi Pelita Mas (STIFA-PM) PaluTraditional medicine is part of the Indonesian cultural heritage which has been used for generations and for centuries, but in general its safety has not been supported by adequate research. One of them is a parangromang which is empirically used by Makassar tribal healers as an antitumor. This study aims to determine theprofile Of body weight and toxic symptoms after 24 hours to 14 days including skin and fur changes, tremors and seizures, comaof rats in the administration of ethanol extract parang romang. White rats were divided randomly into 4 groups: group one was given 0.5% NaCMC, groups of two, three and four were given extract at a dose of 175 mg / KgBB, 550 mg / KgBB and 1750 mg / KgBB for 14 days, the body weights of rats on days 0, 7 and 14 days and toxic symptoms after 24 hours to 14 days.The results showed ethanol extract of parang romang leaves 550 mg / KgBB had an effect on increasing body weight of rats and there were no changes in skin and fur, spasms, tremor, coma and death. It can be concluded that the ethanol extract of parang romang leaves has a significant effect on increasing the weight profile of male white rats and there are no toxic symptoms.https://bestjournal.untad.ac.id/index.php/Galenika/article/view/13928ethanol extractparang romang leavesprofile of body weighttoxic symptomsmale white rat |
| spellingShingle | Magfirah lukman Vidya Christin Analisis Profil Bobot Badan Tikus dan Gejala Toksis Pada Pemberian Ekstrak Etanol Daun Parang Romang (Boehmeria virgata) Terhadap Tikus Putih (Rattus novergicus) Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) ethanol extract parang romang leaves profile of body weight toxic symptoms male white rat |
| title | Analisis Profil Bobot Badan Tikus dan Gejala Toksis Pada Pemberian Ekstrak Etanol Daun Parang Romang (Boehmeria virgata) Terhadap Tikus Putih (Rattus novergicus) |
| title_full | Analisis Profil Bobot Badan Tikus dan Gejala Toksis Pada Pemberian Ekstrak Etanol Daun Parang Romang (Boehmeria virgata) Terhadap Tikus Putih (Rattus novergicus) |
| title_fullStr | Analisis Profil Bobot Badan Tikus dan Gejala Toksis Pada Pemberian Ekstrak Etanol Daun Parang Romang (Boehmeria virgata) Terhadap Tikus Putih (Rattus novergicus) |
| title_full_unstemmed | Analisis Profil Bobot Badan Tikus dan Gejala Toksis Pada Pemberian Ekstrak Etanol Daun Parang Romang (Boehmeria virgata) Terhadap Tikus Putih (Rattus novergicus) |
| title_short | Analisis Profil Bobot Badan Tikus dan Gejala Toksis Pada Pemberian Ekstrak Etanol Daun Parang Romang (Boehmeria virgata) Terhadap Tikus Putih (Rattus novergicus) |
| title_sort | analisis profil bobot badan tikus dan gejala toksis pada pemberian ekstrak etanol daun parang romang boehmeria virgata terhadap tikus putih rattus novergicus |
| topic | ethanol extract parang romang leaves profile of body weight toxic symptoms male white rat |
| url | https://bestjournal.untad.ac.id/index.php/Galenika/article/view/13928 |
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