Associations Between Cardiorespiratory Fitness, Cardiovascular Risk, and Cognition Are Mediated by Structural Brain Health in Midlife

Associations Between Cardiorespiratory Fitness, Cardiovascular Risk, and Cognition Are Mediated by Structural Brain Health in Midlife

Background Evidence in older adults suggests that higher cardiorespiratory fitness and lower cardiovascular risk are associated with greater cognition. However, given that changes in the brain that lead to cognitive decline begin decades before the onset of symptoms, understanding the mechanisms by...

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Bibliographic Details
Main Authors: Goretti España‐Irla, Joyce Gomes‐Osman, Gabriele Cattaneo, Sergiu Albu, María Cabello‐Toscano, Javier Solana‐Sanchéz, María Redondo‐Camós, Selma Delgado‐Gallén, Vanessa Alviarez‐Schulze, Catherine Pachón‐García, Josep M. Tormos, David Bartrés‐Faz, Timothy P. Morris, Álvaro Pascual‐Leone
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
cardiorespiratory fitness
cardiovascular health
cognition
exercise
mediation
midlife
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.120.020688

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