Fluid hydration to prevent post-ERCP pancreatitis in average- to high-risk patients receiving prophylactic rectal NSAIDs (FLUYT trial): study protocol for a randomized controlled trial

Fluid hydration to prevent post-ERCP pancreatitis in average- to high-risk patients receiving prophylactic rectal NSAIDs (FLUYT trial): study protocol for a randomized controlled trial

Abstract Background Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) is the most common complication of ERCP and may run a severe course. Evidence suggests that vigorous periprocedural hydration can prevent PEP, but studies to date have significant methodological drawbac...

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Bibliographic Details
Main Authors: Xavier J. N. M. Smeets, David W. da Costa, Paul Fockens, Chris J. J. Mulder, Robin Timmer, Wietske Kievit, Marieke Zegers, Marco J. Bruno, Marc G. H. Besselink, Frank P. Vleggaar, Rene W. M. van der Hulst, Alexander C. Poen, Gerbrand D. N. Heine, Niels G. Venneman, Jeroen J. Kolkman, Lubbertus C. Baak, Tessa E. H. Römkens, Sven M. van Dijk, Nora D. L. Hallensleben, Wim van de Vrie, Tom C. J. Seerden, Adriaan C. I. T. L. Tan, Annet M. C. J. Voorburg, Jan-Werner Poley, Ben J. Witteman, Abha Bhalla, Muhammed Hadithi, Willem J. Thijs, Matthijs P. Schwartz, Jan Maarten Vrolijk, Robert C. Verdonk, Foke van Delft, Yolande Keulemans, Harry van Goor, Joost P. H. Drenth, Erwin J. M. van Geenen, for the Dutch Pancreatitis Study Group
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Trials
Subjects:
Post-ERCP pancreatitis
Prevention
ERCP
Hydration
NSAIDs
Online Access:http://link.springer.com/article/10.1186/s13063-018-2583-x

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