Dairy Product Consumption and Oligo-Astheno-Teratozoospermia Risk: A Hospital-Based Case-Control Study in China
Background: Researches on the association of dairy products consumption with Oligo-astheno-teratozoospermia (OAT) risk has been limited and controversial. Therefore, we aim to explore the aforementioned association among Chinese men.Methods: A hospital-based case-control study was conducted in men c...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-12-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2021.742375/full |
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| author | Xiao-Bin Wang Qi-Jun Wu Qi-Jun Wu Ren-Hao Guo Xu Leng Qiang Du Yu-Hong Zhao Yu-Hong Zhao Bo-Chen Pan |
| author_facet | Xiao-Bin Wang Qi-Jun Wu Qi-Jun Wu Ren-Hao Guo Xu Leng Qiang Du Yu-Hong Zhao Yu-Hong Zhao Bo-Chen Pan |
| author_sort | Xiao-Bin Wang |
| collection | DOAJ |
| description | Background: Researches on the association of dairy products consumption with Oligo-astheno-teratozoospermia (OAT) risk has been limited and controversial. Therefore, we aim to explore the aforementioned association among Chinese men.Methods: A hospital-based case-control study was conducted in men consisting of 106 cases of OAT and 581 controls. Intakes of dairy products and their related nutrients were collected using a semi-quantitative food frequency questionnaire and semen quality was analyzed according to the World Health Organization guidelines. The daily intake of dairy products and their related nutrients was categorized into three groups with the lowest tertile serving as the reference category. Odds ratios (ORs) and 95% confidence intervals (CIs) of association between dairy intake and OTA risk were calculated by the multivariable logistic regression models.Results: No significant association was found between total dairy (OR T3vs.T1 =1.53, 95% CI: 0.85–2.78), protein (OR T3vs.T1 =1.51, 95% CI: 0.84–2.75), or calcium (OR T3vs.T1 = 1.46, 95% CI: 0.81–2.66) and the OAT risk in the main findings. However, we observed a statistically significant positive association of dairy fat intake with OAT risk (OR T3vs.T1 =1.93, 95% CI: 1.06–3.58). The findings were consistent with the main results when we carried out subgroup analysis stratified by body mass index.Conclusion: A significant positive association was found between dairy fat intake and the risk of OAT. Further large-scale prospective studies are required to confirm this finding. |
| first_indexed | 2024-12-20T15:34:22Z |
| format | Article |
| id | doaj.art-ef5e664bde914cadb5246a58498e6e3f |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-12-20T15:34:22Z |
| publishDate | 2021-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-ef5e664bde914cadb5246a58498e6e3f2022-12-21T19:35:31ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2021-12-01810.3389/fnut.2021.742375742375Dairy Product Consumption and Oligo-Astheno-Teratozoospermia Risk: A Hospital-Based Case-Control Study in ChinaXiao-Bin Wang0Qi-Jun Wu1Qi-Jun Wu2Ren-Hao Guo3Xu Leng4Qiang Du5Yu-Hong Zhao6Yu-Hong Zhao7Bo-Chen Pan8Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, ChinaClinical Research Center, Shengjing Hospital of China Medical University, Shenyang, ChinaCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, ChinaCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, ChinaCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, ChinaDepartment of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, ChinaClinical Research Center, Shengjing Hospital of China Medical University, Shenyang, ChinaCenter for Reproductive Medicine, Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, ChinaBackground: Researches on the association of dairy products consumption with Oligo-astheno-teratozoospermia (OAT) risk has been limited and controversial. Therefore, we aim to explore the aforementioned association among Chinese men.Methods: A hospital-based case-control study was conducted in men consisting of 106 cases of OAT and 581 controls. Intakes of dairy products and their related nutrients were collected using a semi-quantitative food frequency questionnaire and semen quality was analyzed according to the World Health Organization guidelines. The daily intake of dairy products and their related nutrients was categorized into three groups with the lowest tertile serving as the reference category. Odds ratios (ORs) and 95% confidence intervals (CIs) of association between dairy intake and OTA risk were calculated by the multivariable logistic regression models.Results: No significant association was found between total dairy (OR T3vs.T1 =1.53, 95% CI: 0.85–2.78), protein (OR T3vs.T1 =1.51, 95% CI: 0.84–2.75), or calcium (OR T3vs.T1 = 1.46, 95% CI: 0.81–2.66) and the OAT risk in the main findings. However, we observed a statistically significant positive association of dairy fat intake with OAT risk (OR T3vs.T1 =1.93, 95% CI: 1.06–3.58). The findings were consistent with the main results when we carried out subgroup analysis stratified by body mass index.Conclusion: A significant positive association was found between dairy fat intake and the risk of OAT. Further large-scale prospective studies are required to confirm this finding.https://www.frontiersin.org/articles/10.3389/fnut.2021.742375/fullassociationcase-control studyChinadairy productoligo-astheno-teratozoospermia |
| spellingShingle | Xiao-Bin Wang Qi-Jun Wu Qi-Jun Wu Ren-Hao Guo Xu Leng Qiang Du Yu-Hong Zhao Yu-Hong Zhao Bo-Chen Pan Dairy Product Consumption and Oligo-Astheno-Teratozoospermia Risk: A Hospital-Based Case-Control Study in China Frontiers in Nutrition association case-control study China dairy product oligo-astheno-teratozoospermia |
| title | Dairy Product Consumption and Oligo-Astheno-Teratozoospermia Risk: A Hospital-Based Case-Control Study in China |
| title_full | Dairy Product Consumption and Oligo-Astheno-Teratozoospermia Risk: A Hospital-Based Case-Control Study in China |
| title_fullStr | Dairy Product Consumption and Oligo-Astheno-Teratozoospermia Risk: A Hospital-Based Case-Control Study in China |
| title_full_unstemmed | Dairy Product Consumption and Oligo-Astheno-Teratozoospermia Risk: A Hospital-Based Case-Control Study in China |
| title_short | Dairy Product Consumption and Oligo-Astheno-Teratozoospermia Risk: A Hospital-Based Case-Control Study in China |
| title_sort | dairy product consumption and oligo astheno teratozoospermia risk a hospital based case control study in china |
| topic | association case-control study China dairy product oligo-astheno-teratozoospermia |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2021.742375/full |
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