Identification of putative essential protein domains from high-density transposon insertion sequencing

Abstract A first clue to gene function can be obtained by examining whether a gene is required for life in certain standard conditions, that is, whether a gene is essential. In bacteria, essential genes are usually identified by high-density transposon mutagenesis followed by sequencing of insertion...

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Bibliographic Details
Main Authors: A. S. M. Zisanur Rahman, Lukas Timmerman, Flyn Gallardo, Silvia T. Cardona
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05028-x