An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds

Benzimidazole, a benzene-fused heterocyclic compound, has acquired significant attention in the field of contemporary medicinal chemistry because of its wide array of pharmacological activities. Nitrogen containing heterocyclic compounds are part of several therapeutically important agents with seve...

Full description

Bibliographic Details
Main Authors: Heba E. Hashem, Youness El Bakri
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221004330
_version_ 1830194100366737408
author Heba E. Hashem
Youness El Bakri
author_facet Heba E. Hashem
Youness El Bakri
author_sort Heba E. Hashem
collection DOAJ
description Benzimidazole, a benzene-fused heterocyclic compound, has acquired significant attention in the field of contemporary medicinal chemistry because of its wide array of pharmacological activities. Nitrogen containing heterocyclic compounds are part of several therapeutically important agents with several recent patents shedding light on their worth. For these reasons, this review is concerned with different methods for synthesis of benzimidazole derivatives and their biological importance.
first_indexed 2024-12-18T00:23:49Z
format Article
id doaj.art-ef608dd4a54649b8962e3d8191a0e074
institution Directory Open Access Journal
issn 1878-5352
language English
last_indexed 2024-12-18T00:23:49Z
publishDate 2021-11-01
publisher Elsevier
record_format Article
series Arabian Journal of Chemistry
spelling doaj.art-ef608dd4a54649b8962e3d8191a0e0742022-12-21T21:27:17ZengElsevierArabian Journal of Chemistry1878-53522021-11-011411103418An overview on novel synthetic approaches and medicinal applications of benzimidazole compoundsHeba E. Hashem0Youness El Bakri1Department of Chemistry, Faculty of Women, Ain Shams University, Heliopolis, Cairo 11757, Egypt; Corresponding author.Department of Theoretical and Applied Chemistry, South Ural State University, Lenin prospect 76, Chelyabinsk 454080, Russian FederationBenzimidazole, a benzene-fused heterocyclic compound, has acquired significant attention in the field of contemporary medicinal chemistry because of its wide array of pharmacological activities. Nitrogen containing heterocyclic compounds are part of several therapeutically important agents with several recent patents shedding light on their worth. For these reasons, this review is concerned with different methods for synthesis of benzimidazole derivatives and their biological importance.http://www.sciencedirect.com/science/article/pii/S1878535221004330O-phenylenediaminesBenzimidazolesSynthesisBiological activities
spellingShingle Heba E. Hashem
Youness El Bakri
An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds
Arabian Journal of Chemistry
O-phenylenediamines
Benzimidazoles
Synthesis
Biological activities
title An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds
title_full An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds
title_fullStr An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds
title_full_unstemmed An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds
title_short An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds
title_sort overview on novel synthetic approaches and medicinal applications of benzimidazole compounds
topic O-phenylenediamines
Benzimidazoles
Synthesis
Biological activities
url http://www.sciencedirect.com/science/article/pii/S1878535221004330
work_keys_str_mv AT hebaehashem anoverviewonnovelsyntheticapproachesandmedicinalapplicationsofbenzimidazolecompounds
AT younesselbakri anoverviewonnovelsyntheticapproachesandmedicinalapplicationsofbenzimidazolecompounds
AT hebaehashem overviewonnovelsyntheticapproachesandmedicinalapplicationsofbenzimidazolecompounds
AT younesselbakri overviewonnovelsyntheticapproachesandmedicinalapplicationsofbenzimidazolecompounds