Long-Term Outcomes of a Kahook Dual Blade Procedure Combined with Phacoemulsification in Japanese Patients with Open-Angle Glaucoma

We retrospectively evaluated the long-term surgical outcomes of phacoemulsification combined with a Kahook dual blade (KDB) procedure in Japanese patients with open-angle glaucoma. The primary outcome was surgical success or failure. Surgical failure was indicated by a <20% reduction in preoperat...

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Main Authors: Kentaro Iwasaki, Hiroshi Kakimoto, Yusuke Orii, Shogo Arimura, Yoshihiro Takamura, Masaru Inatani
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/5/1354
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author Kentaro Iwasaki
Hiroshi Kakimoto
Yusuke Orii
Shogo Arimura
Yoshihiro Takamura
Masaru Inatani
author_facet Kentaro Iwasaki
Hiroshi Kakimoto
Yusuke Orii
Shogo Arimura
Yoshihiro Takamura
Masaru Inatani
author_sort Kentaro Iwasaki
collection DOAJ
description We retrospectively evaluated the long-term surgical outcomes of phacoemulsification combined with a Kahook dual blade (KDB) procedure in Japanese patients with open-angle glaucoma. The primary outcome was surgical success or failure. Surgical failure was indicated by a <20% reduction in preoperative intraocular pressure (IOP) or IOP > 18 mmHg (criterion A), IOP > 14 mmHg (criterion B), or requirement for reoperation. Glaucoma medications after surgery and postoperative complications were recorded. Surgical outcomes were compared between primary open-angle glaucoma (POAG) and exfoliation glaucoma (ExG) groups. The probability of success at 36 months postoperation was 52.5% using criterion A and 36.9% using criterion B. Mean IOP decreased significantly from 19.5 ± 6.9 mmHg preoperatively to 11.9 ± 2.7 mmHg at 36 months, and the mean number of glaucoma medications from 2.4 ± 1.4 to 1.6 ± 1.4 (both <i>p</i> < 0.01). IOP spikes were significantly more common in the ExG group (23.7% vs. 9.1%; <i>p</i> = 0.045), as was the need for additional glaucoma surgery (10.5% vs. 1.8%; <i>p</i> = 0.038). A KDB procedure combined with cataract surgery resulted in significant long-term decreases in IOP and the number of glaucoma medications. The complication rate was higher in eyes with ExG. Therefore, these eyes require more careful management after a KDB procedure.
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spelling doaj.art-ef64b44a656d4caf830b1e586e140b5c2023-11-23T23:14:36ZengMDPI AGJournal of Clinical Medicine2077-03832022-03-01115135410.3390/jcm11051354Long-Term Outcomes of a Kahook Dual Blade Procedure Combined with Phacoemulsification in Japanese Patients with Open-Angle GlaucomaKentaro Iwasaki0Hiroshi Kakimoto1Yusuke Orii2Shogo Arimura3Yoshihiro Takamura4Masaru Inatani5Department of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Obama Hospital, Fukui 917-0078, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanDepartment of Ophthalmology, Faculty of Medical Sciences, University of Fukui, Fukui 910-1193, JapanWe retrospectively evaluated the long-term surgical outcomes of phacoemulsification combined with a Kahook dual blade (KDB) procedure in Japanese patients with open-angle glaucoma. The primary outcome was surgical success or failure. Surgical failure was indicated by a <20% reduction in preoperative intraocular pressure (IOP) or IOP > 18 mmHg (criterion A), IOP > 14 mmHg (criterion B), or requirement for reoperation. Glaucoma medications after surgery and postoperative complications were recorded. Surgical outcomes were compared between primary open-angle glaucoma (POAG) and exfoliation glaucoma (ExG) groups. The probability of success at 36 months postoperation was 52.5% using criterion A and 36.9% using criterion B. Mean IOP decreased significantly from 19.5 ± 6.9 mmHg preoperatively to 11.9 ± 2.7 mmHg at 36 months, and the mean number of glaucoma medications from 2.4 ± 1.4 to 1.6 ± 1.4 (both <i>p</i> < 0.01). IOP spikes were significantly more common in the ExG group (23.7% vs. 9.1%; <i>p</i> = 0.045), as was the need for additional glaucoma surgery (10.5% vs. 1.8%; <i>p</i> = 0.038). A KDB procedure combined with cataract surgery resulted in significant long-term decreases in IOP and the number of glaucoma medications. The complication rate was higher in eyes with ExG. Therefore, these eyes require more careful management after a KDB procedure.https://www.mdpi.com/2077-0383/11/5/1354Kahook dual bladephacoemulsificationopen-angle glaucomasurgical efficacysurgical complication
spellingShingle Kentaro Iwasaki
Hiroshi Kakimoto
Yusuke Orii
Shogo Arimura
Yoshihiro Takamura
Masaru Inatani
Long-Term Outcomes of a Kahook Dual Blade Procedure Combined with Phacoemulsification in Japanese Patients with Open-Angle Glaucoma
Journal of Clinical Medicine
Kahook dual blade
phacoemulsification
open-angle glaucoma
surgical efficacy
surgical complication
title Long-Term Outcomes of a Kahook Dual Blade Procedure Combined with Phacoemulsification in Japanese Patients with Open-Angle Glaucoma
title_full Long-Term Outcomes of a Kahook Dual Blade Procedure Combined with Phacoemulsification in Japanese Patients with Open-Angle Glaucoma
title_fullStr Long-Term Outcomes of a Kahook Dual Blade Procedure Combined with Phacoemulsification in Japanese Patients with Open-Angle Glaucoma
title_full_unstemmed Long-Term Outcomes of a Kahook Dual Blade Procedure Combined with Phacoemulsification in Japanese Patients with Open-Angle Glaucoma
title_short Long-Term Outcomes of a Kahook Dual Blade Procedure Combined with Phacoemulsification in Japanese Patients with Open-Angle Glaucoma
title_sort long term outcomes of a kahook dual blade procedure combined with phacoemulsification in japanese patients with open angle glaucoma
topic Kahook dual blade
phacoemulsification
open-angle glaucoma
surgical efficacy
surgical complication
url https://www.mdpi.com/2077-0383/11/5/1354
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