Kinetics of hydrolysis of 1,4-benzodiazepine derivative by carboxylesterases in mice organism
Chemical modification of the physiologically active substances and creation of prodrugs is one of the ways for pharmacotherapy optimization. The aim of the work was determination of the kinetic parameters of nonspecific esterases that catalyze hydrolysis of new hypnotic drug Levana (1,4-benzodiazepi...
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| Format: | Article |
| Language: | English |
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National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2014-08-01
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| Series: | The Ukrainian Biochemical Journal |
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| Online Access: | http://ukrbiochemjournal.org/wp-content/uploads/2015/06/Golovenko_4_14.pdf |