Novel multifunctional nanoliposomes inhibit α-synuclein fibrillization, attenuate microglial activation, and silence the expression of SNCA gene
Introduction: The aim of this study was to compare the effect of five types of PEGlated nanoliposomes (PNLs) on α-synuclein (α-syn) fibrillization, attenuation of microglial activation, and silence of the SNCA gene, which encodes α-syn. Methods: To evaluate the inhibition of α-syn fibrillization, we...
Main Authors: | A. Jebali, M. Rashidi, R. Keikha, K. Daliri, T.F. Outeiro |
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Format: | Article |
Language: | English |
Published: |
Elsevier España
2024-05-01
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Series: | Neurología (English Edition) |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2173580824000348 |
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