Novel multifunctional nanoliposomes inhibit α-synuclein fibrillization, attenuate microglial activation, and silence the expression of SNCA gene

Introduction: The aim of this study was to compare the effect of five types of PEGlated nanoliposomes (PNLs) on α-synuclein (α-syn) fibrillization, attenuation of microglial activation, and silence of the SNCA gene, which encodes α-syn. Methods: To evaluate the inhibition of α-syn fibrillization, we...

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Bibliographic Details
Main Authors: A. Jebali, M. Rashidi, R. Keikha, K. Daliri, T.F. Outeiro
Format: Article
Language:English
Published: Elsevier España 2024-05-01
Series:Neurología (English Edition)
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Online Access:http://www.sciencedirect.com/science/article/pii/S2173580824000348

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