Presenilin-1 Protects against Neuronal Apoptosis Caused by Its Interacting Protein PAG

Presenilin-1 Protects against Neuronal Apoptosis Caused by Its Interacting Protein PAG

Mutations in the presenilin-1 (PS-1) gene account for a significant fraction of familial Alzheimer's disease. The biological function of PS-1 is not well understood. We report here that the proliferation-associated gene (PAG) product, a protein of the thioredoxin peroxidase family, interacts wi...

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Bibliographic Details
Main Authors: Yan Zhou, Wanjiang Zhang, Rachael Easton, James W. Ray, Patricia Lampe, Zhihong Jiang, Anne L. Brunkan, Alison Goate, Eugene M. Johnson, Jane Y. Wu
Format: Article
Language:English
Published: Elsevier 2002-03-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996101904723

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