Effect of Selenium nanoparticles antioxidant on sperm parameters in mature and adult rats
Background & Objective: Selenium is often caused selenoproteins, which is using in the construction of antioxidant enzymes that are necessary for the health of those cells which are subjected to oxidative stress-induced. Due to its antioxidant properties, selenium is an essential and rare elemen...
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| Format: | Article |
| Language: | English |
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Fasa University of Medical Sciences
2014-05-01
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| Series: | Journal of Advanced Biomedical Sciences |
| Subjects: | |
| Online Access: | http://jabs.fums.ac.ir/article-1-305-en.pdf |
| _version_ | 1797679727506358272 |
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| author | Habibeh ghazanfarpoor Ebrahim Talebi Farangis Ghasemi Marjan Haghigat Jahromi |
| author_facet | Habibeh ghazanfarpoor Ebrahim Talebi Farangis Ghasemi Marjan Haghigat Jahromi |
| author_sort | Habibeh ghazanfarpoor |
| collection | DOAJ |
| description | Background & Objective: Selenium is often caused selenoproteins, which is using in the construction of antioxidant enzymes that are necessary for the health of those cells which are subjected to oxidative stress-induced. Due to its antioxidant properties, selenium is an essential and rare element for spermatogenesis and sperm characteristics, especially in the late reproductive age. Therefore, in this study, the role of selenium nanoparticles was investigated on semen parameters in young and adult rats.
Materials & Methods: Mature male Wistar rats (2-3 months old) and the adult ones (10-12 months), are divided into 4 groups where 5 animals per each group are put (control, testifier and experimental groups). The experimental rats received Selenium Nano particles through stomach tube for 35 days, each day different doses of 0.2 and 0.4 mg/kg of their body weight. . After this period, the semen parameters in both mature and adult rat were compared.
Results: The spermatozoa count, sperm motility and viability, increased particularly in adult rats which used 0.04 mg/kg body weight nano selenium and the number of dead and damaged Spermatozoa are significantly reduced (p<0.05). The Percentage of sperm cell injury increased significantly in young rats in the group that received a dose of 0.04 mg of selenium nanoparticles.
Conclusions: These findings suggest that administration of Nano-Selenium improves the sperm parameters during the spermatogenesis. |
| first_indexed | 2024-03-11T23:19:05Z |
| format | Article |
| id | doaj.art-ef6ffb479bf24f8fa72ea19f8e5107b3 |
| institution | Directory Open Access Journal |
| issn | 2228-5105 2783-1523 |
| language | English |
| last_indexed | 2024-03-11T23:19:05Z |
| publishDate | 2014-05-01 |
| publisher | Fasa University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Biomedical Sciences |
| spelling | doaj.art-ef6ffb479bf24f8fa72ea19f8e5107b32023-09-20T21:17:19ZengFasa University of Medical SciencesJournal of Advanced Biomedical Sciences2228-51052783-15232014-05-0141111119Effect of Selenium nanoparticles antioxidant on sperm parameters in mature and adult ratsHabibeh ghazanfarpoor0Ebrahim Talebi1Farangis Ghasemi2Marjan Haghigat Jahromi3 Jahrom Branch, Islamic Azad University, Jahrom, Fars, Iran Darab Branch, Islamic Azad University Jahrom Branch, Islamic Azad University, Jahrom, Fars, Iran Background & Objective: Selenium is often caused selenoproteins, which is using in the construction of antioxidant enzymes that are necessary for the health of those cells which are subjected to oxidative stress-induced. Due to its antioxidant properties, selenium is an essential and rare element for spermatogenesis and sperm characteristics, especially in the late reproductive age. Therefore, in this study, the role of selenium nanoparticles was investigated on semen parameters in young and adult rats. Materials & Methods: Mature male Wistar rats (2-3 months old) and the adult ones (10-12 months), are divided into 4 groups where 5 animals per each group are put (control, testifier and experimental groups). The experimental rats received Selenium Nano particles through stomach tube for 35 days, each day different doses of 0.2 and 0.4 mg/kg of their body weight. . After this period, the semen parameters in both mature and adult rat were compared. Results: The spermatozoa count, sperm motility and viability, increased particularly in adult rats which used 0.04 mg/kg body weight nano selenium and the number of dead and damaged Spermatozoa are significantly reduced (p<0.05). The Percentage of sperm cell injury increased significantly in young rats in the group that received a dose of 0.04 mg of selenium nanoparticles. Conclusions: These findings suggest that administration of Nano-Selenium improves the sperm parameters during the spermatogenesis.http://jabs.fums.ac.ir/article-1-305-en.pdfoxidative stresssperm parameternano seleniumspermatogenesis |
| spellingShingle | Habibeh ghazanfarpoor Ebrahim Talebi Farangis Ghasemi Marjan Haghigat Jahromi Effect of Selenium nanoparticles antioxidant on sperm parameters in mature and adult rats Journal of Advanced Biomedical Sciences oxidative stress sperm parameter nano selenium spermatogenesis |
| title | Effect of Selenium nanoparticles antioxidant on sperm parameters in mature and adult rats |
| title_full | Effect of Selenium nanoparticles antioxidant on sperm parameters in mature and adult rats |
| title_fullStr | Effect of Selenium nanoparticles antioxidant on sperm parameters in mature and adult rats |
| title_full_unstemmed | Effect of Selenium nanoparticles antioxidant on sperm parameters in mature and adult rats |
| title_short | Effect of Selenium nanoparticles antioxidant on sperm parameters in mature and adult rats |
| title_sort | effect of selenium nanoparticles antioxidant on sperm parameters in mature and adult rats |
| topic | oxidative stress sperm parameter nano selenium spermatogenesis |
| url | http://jabs.fums.ac.ir/article-1-305-en.pdf |
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