Obesity-Associated Alterations of Natural Killer Cells and Immunosurveillance of Cancer

Obesity-Associated Alterations of Natural Killer Cells and Immunosurveillance of Cancer

Obesity is accompanied by a systemic chronic low-grade inflammation as well as dysfunctions of several innate and adaptive immune cells. Recent findings emphasize an impaired functionality and phenotype of natural killer (NK) cells under obese conditions. This review provides a detailed overview on...

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Bibliographic Details
Main Authors: Ina Bähr, Julia Spielmann, Dagmar Quandt, Heike Kielstein
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
NK cells
obesity
adipokines
inflammation
cancer
prevention
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00245/full

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