Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model

Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model

Radiation exposure causes acute damage to hematopoietic and immune cells. To date, there are no radioprotectors available to mitigate hematopoietic injury after radiation exposure. Gamma-tocotrienol (GT3) has demonstrated promising radioprotective efficacy in the mouse and nonhuman primate (NHP) mod...

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Bibliographic Details
Main Authors: Tarun K. Garg, Sarita Garg, Isabelle R. Miousse, Stephen Y. Wise, Alana D. Carpenter, Oluseyi O. Fatanmi, Frits van Rhee, Vijay K. Singh, Martin Hauer-Jensen
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
colony-forming units
gamma-tocotrienol
hematopoietic progenitors
nonhuman primates
radiation countermeasure
total-body irradiation
Online Access:https://www.mdpi.com/1422-0067/23/24/16170

Internet

https://www.mdpi.com/1422-0067/23/24/16170

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