NDV-induced autophagy enhances inflammation through NLRP3/Caspase-1 inflammasomes and the p38/MAPK pathway

NDV-induced autophagy enhances inflammation through NLRP3/Caspase-1 inflammasomes and the p38/MAPK pathway

Abstract Newcastle disease (ND), caused by the Newcastle disease virus (NDV), is a highly virulent infectious disease of poultry. Virulent NDV can cause severe autophagy and inflammation in host cells. While studies have shown a mutual regulatory relationship between autophagy and inflammation, this...

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Bibliographic Details
Main Authors: Juncheng Cai, Siyuan Wang, Haoyun Du, Lei Fan, WeiFeng Yuan, Qiufan Xu, Jinlian Ren, Qiuyan Lin, Bin Xiang, Chan Ding, Tao Ren, Libin Chen
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Veterinary Research
Subjects:
Autophagy
inflammation
mitochondrial damage
mitophagy
Newcastle disease virus
Online Access:https://doi.org/10.1186/s13567-023-01174-w

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