Emergence of a Unique Group of Necrotizing Mycobacterial Diseases
Although most diseases due to pathogenic mycobacteria are caused by Mycobacterium tuberculosis, several other mycobacterial diseases—caused by M. ulcerans (Buruli ulcer), M. marinum, and M. haemophilum—have begun to emerge. We review the emergence of diseases caused by these three pathogens in the U...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
1999-06-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/5/3/99-0307_article |
| _version_ | 1818017799692353536 |
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| author | Karen M. Dobos Frederick D. Quinn David A. Ashford C. Robert Horsburgh C. Harold King |
| author_facet | Karen M. Dobos Frederick D. Quinn David A. Ashford C. Robert Horsburgh C. Harold King |
| author_sort | Karen M. Dobos |
| collection | DOAJ |
| description | Although most diseases due to pathogenic mycobacteria are caused by Mycobacterium tuberculosis, several other mycobacterial diseases—caused by M. ulcerans (Buruli ulcer), M. marinum, and M. haemophilum—have begun to emerge. We review the emergence of diseases caused by these three pathogens in the United States and around the world in the last decade. We examine the pathophysiologic similarities of the diseases (all three cause necrotizing skin lesions) and common reservoirs of infection (stagnant or slow-flowing water). Examination of the histologic and pathogenic characteristics of these mycobacteria suggests differences in the modes of transmission and pathogenesis, though no singular mechanism for either characteristic has been definitively described for any of these mycobacteria. |
| first_indexed | 2024-04-14T07:31:32Z |
| format | Article |
| id | doaj.art-ef788ef782d044ba9885b1331d87263b |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-14T07:31:32Z |
| publishDate | 1999-06-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-ef788ef782d044ba9885b1331d87263b2022-12-22T02:05:51ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60591999-06-015336737810.3201/eid0503.990307Emergence of a Unique Group of Necrotizing Mycobacterial DiseasesKaren M. DobosFrederick D. QuinnDavid A. AshfordC. Robert HorsburghC. Harold KingAlthough most diseases due to pathogenic mycobacteria are caused by Mycobacterium tuberculosis, several other mycobacterial diseases—caused by M. ulcerans (Buruli ulcer), M. marinum, and M. haemophilum—have begun to emerge. We review the emergence of diseases caused by these three pathogens in the United States and around the world in the last decade. We examine the pathophysiologic similarities of the diseases (all three cause necrotizing skin lesions) and common reservoirs of infection (stagnant or slow-flowing water). Examination of the histologic and pathogenic characteristics of these mycobacteria suggests differences in the modes of transmission and pathogenesis, though no singular mechanism for either characteristic has been definitively described for any of these mycobacteria.https://wwwnc.cdc.gov/eid/article/5/3/99-0307_articleUnited States |
| spellingShingle | Karen M. Dobos Frederick D. Quinn David A. Ashford C. Robert Horsburgh C. Harold King Emergence of a Unique Group of Necrotizing Mycobacterial Diseases Emerging Infectious Diseases United States |
| title | Emergence of a Unique Group of Necrotizing Mycobacterial Diseases |
| title_full | Emergence of a Unique Group of Necrotizing Mycobacterial Diseases |
| title_fullStr | Emergence of a Unique Group of Necrotizing Mycobacterial Diseases |
| title_full_unstemmed | Emergence of a Unique Group of Necrotizing Mycobacterial Diseases |
| title_short | Emergence of a Unique Group of Necrotizing Mycobacterial Diseases |
| title_sort | emergence of a unique group of necrotizing mycobacterial diseases |
| topic | United States |
| url | https://wwwnc.cdc.gov/eid/article/5/3/99-0307_article |
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