Cotranslational microRNA mediated messenger RNA destabilization

Cotranslational microRNA mediated messenger RNA destabilization

MicroRNAs are small (22 nucleotide) regulatory molecules that play important roles in a wide variety of biological processes. These RNAs, which bind to targeted mRNAs via limited base pairing interactions, act to reduce protein production from those mRNAs. Considerable evidence indicates that miRNAs...

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Bibliographic Details
Main Authors: Trinh To Tat, Patricia A Maroney, Sangpen Chamnongpol, Jeff Coller, Timothy W Nilsen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-04-01
Series:eLife
Subjects:
microRNAs
mRNA decay
cotranslation
Online Access:https://elifesciences.org/articles/12880

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