Research progress of autophagy and diabetic retinopathy
Diabetic retinopathy(DR)is one of the most serious complicationsand leading causes of blindness for diabetic patients. In recent years, the incidence of DR shows a trend of rising year by year, which is a serious threat to the patients' physical and mental health. Autophagy is a very important...
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Format: | Article |
Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2017-03-01
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Series: | Guoji Yanke Zazhi |
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Online Access: | http://ies.ijo.cn/cn_publish/2017/3/201703015.pdf |
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author | Jun-Hui Du Rong Li undefined |
author_facet | Jun-Hui Du Rong Li undefined |
author_sort | Jun-Hui Du |
collection | DOAJ |
description | Diabetic retinopathy(DR)is one of the most serious complicationsand leading causes of blindness for diabetic patients. In recent years, the incidence of DR shows a trend of rising year by year, which is a serious threat to the patients' physical and mental health. Autophagy is a very important physiological process that the cellular contents are processed by the primary lysosomes when the body is under the environment of substance and energy metabolism disorder. Autophagy belongs to one kind of the body's important defense mechanisms. According to the related clinical research data, autophagy can delay the occurrence and development of the chronic complications of diabetes to some extent, such as DR, peripheral neuropathy and diabetic nephropathy. There is a close relationship between autophagy and various relative factors of DR, such as oxidative stress and hypoxia. Therefore, the pathogenesis and treatment measures of DR have become critical research topics in clinical practice. |
first_indexed | 2024-04-13T10:52:52Z |
format | Article |
id | doaj.art-ef7dba4610064de5bd254526f7173205 |
institution | Directory Open Access Journal |
issn | 1672-5123 1672-5123 |
language | English |
last_indexed | 2024-04-13T10:52:52Z |
publishDate | 2017-03-01 |
publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
record_format | Article |
series | Guoji Yanke Zazhi |
spelling | doaj.art-ef7dba4610064de5bd254526f71732052022-12-22T02:49:37ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232017-03-0117345145310.3980/j.issn.1672-5123.2017.3.15Research progress of autophagy and diabetic retinopathyJun-Hui Du0Rong Li1undefined2Department of Ophthalmology, Xi'an Ninth Hospital,Xi'an 710054, Shaanxi Province, ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xi'an Medical University, Xi'an 710077, Shaanxi Province, ChinaSchool of Public Health, Xi'an Jiaotong University College of Public Health, Xi'an 710061, Shaanxi Province, ChinaDiabetic retinopathy(DR)is one of the most serious complicationsand leading causes of blindness for diabetic patients. In recent years, the incidence of DR shows a trend of rising year by year, which is a serious threat to the patients' physical and mental health. Autophagy is a very important physiological process that the cellular contents are processed by the primary lysosomes when the body is under the environment of substance and energy metabolism disorder. Autophagy belongs to one kind of the body's important defense mechanisms. According to the related clinical research data, autophagy can delay the occurrence and development of the chronic complications of diabetes to some extent, such as DR, peripheral neuropathy and diabetic nephropathy. There is a close relationship between autophagy and various relative factors of DR, such as oxidative stress and hypoxia. Therefore, the pathogenesis and treatment measures of DR have become critical research topics in clinical practice.http://ies.ijo.cn/cn_publish/2017/3/201703015.pdfautophagydiabetic retinopathyreviewreview |
spellingShingle | Jun-Hui Du Rong Li undefined Research progress of autophagy and diabetic retinopathy Guoji Yanke Zazhi autophagy diabetic retinopathy review review |
title | Research progress of autophagy and diabetic retinopathy |
title_full | Research progress of autophagy and diabetic retinopathy |
title_fullStr | Research progress of autophagy and diabetic retinopathy |
title_full_unstemmed | Research progress of autophagy and diabetic retinopathy |
title_short | Research progress of autophagy and diabetic retinopathy |
title_sort | research progress of autophagy and diabetic retinopathy |
topic | autophagy diabetic retinopathy review review |
url | http://ies.ijo.cn/cn_publish/2017/3/201703015.pdf |
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