Research progress of autophagy and diabetic retinopathy

Diabetic retinopathy(DR)is one of the most serious complicationsand leading causes of blindness for diabetic patients. In recent years, the incidence of DR shows a trend of rising year by year, which is a serious threat to the patients' physical and mental health. Autophagy is a very important...

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Main Authors: Jun-Hui Du, Rong Li, undefined
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2017-03-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2017/3/201703015.pdf
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author Jun-Hui Du
Rong Li
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author_facet Jun-Hui Du
Rong Li
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author_sort Jun-Hui Du
collection DOAJ
description Diabetic retinopathy(DR)is one of the most serious complicationsand leading causes of blindness for diabetic patients. In recent years, the incidence of DR shows a trend of rising year by year, which is a serious threat to the patients' physical and mental health. Autophagy is a very important physiological process that the cellular contents are processed by the primary lysosomes when the body is under the environment of substance and energy metabolism disorder. Autophagy belongs to one kind of the body's important defense mechanisms. According to the related clinical research data, autophagy can delay the occurrence and development of the chronic complications of diabetes to some extent, such as DR, peripheral neuropathy and diabetic nephropathy. There is a close relationship between autophagy and various relative factors of DR, such as oxidative stress and hypoxia. Therefore, the pathogenesis and treatment measures of DR have become critical research topics in clinical practice.
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spelling doaj.art-ef7dba4610064de5bd254526f71732052022-12-22T02:49:37ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232017-03-0117345145310.3980/j.issn.1672-5123.2017.3.15Research progress of autophagy and diabetic retinopathyJun-Hui Du0Rong Li1undefined2Department of Ophthalmology, Xi'an Ninth Hospital,Xi'an 710054, Shaanxi Province, ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Xi'an Medical University, Xi'an 710077, Shaanxi Province, ChinaSchool of Public Health, Xi'an Jiaotong University College of Public Health, Xi'an 710061, Shaanxi Province, ChinaDiabetic retinopathy(DR)is one of the most serious complicationsand leading causes of blindness for diabetic patients. In recent years, the incidence of DR shows a trend of rising year by year, which is a serious threat to the patients' physical and mental health. Autophagy is a very important physiological process that the cellular contents are processed by the primary lysosomes when the body is under the environment of substance and energy metabolism disorder. Autophagy belongs to one kind of the body's important defense mechanisms. According to the related clinical research data, autophagy can delay the occurrence and development of the chronic complications of diabetes to some extent, such as DR, peripheral neuropathy and diabetic nephropathy. There is a close relationship between autophagy and various relative factors of DR, such as oxidative stress and hypoxia. Therefore, the pathogenesis and treatment measures of DR have become critical research topics in clinical practice.http://ies.ijo.cn/cn_publish/2017/3/201703015.pdfautophagydiabetic retinopathyreviewreview
spellingShingle Jun-Hui Du
Rong Li
undefined
Research progress of autophagy and diabetic retinopathy
Guoji Yanke Zazhi
autophagy
diabetic retinopathy
review
review
title Research progress of autophagy and diabetic retinopathy
title_full Research progress of autophagy and diabetic retinopathy
title_fullStr Research progress of autophagy and diabetic retinopathy
title_full_unstemmed Research progress of autophagy and diabetic retinopathy
title_short Research progress of autophagy and diabetic retinopathy
title_sort research progress of autophagy and diabetic retinopathy
topic autophagy
diabetic retinopathy
review
review
url http://ies.ijo.cn/cn_publish/2017/3/201703015.pdf
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