Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)

Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)

General control non-repressible 5 (GCN5)-related N-acetyltransferases (GNAT) catalyze the transfer of an acyl moiety from acyl coenzyme A (acyl-CoA) to a diverse group of substrates and are widely distributed in all domains of life. This review of the currently available data acquired on GNAT enzyme...

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Bibliographic Details
Main Authors: Abu Iftiaf Md Salah Ud-Din, Alexandra Tikhomirova, Anna Roujeinikova
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:International Journal of Molecular Sciences
Subjects:
GNAT
acetyltransferase
crystal structure
reaction mechanism
enzyme inhibitor
catalytic residues
Online Access:http://www.mdpi.com/1422-0067/17/7/1018

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