Chlamydia trachomatis infections and their impact in the adolescent population

Chlamydia trachomatis is an obligate intracellular organism and can only replicate inside eukaryotic host cells. It has a unique developmental cycle, with metabolically inert, spore‑like elementary bodies that infect host cells and develop into metabolically active, replicative or reticulate bodies...

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Main Authors: Martín Santalucía, Alicia Farinati
Format: Article
Language:English
Published: Zeppelini Editorial e Comunicacao 2022-08-01
Series:DST
Subjects:
Online Access:https://bjstd.org/revista/article/view/733
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author Martín Santalucía
Alicia Farinati
author_facet Martín Santalucía
Alicia Farinati
author_sort Martín Santalucía
collection DOAJ
description Chlamydia trachomatis is an obligate intracellular organism and can only replicate inside eukaryotic host cells. It has a unique developmental cycle, with metabolically inert, spore‑like elementary bodies that infect host cells and develop into metabolically active, replicative or reticulate bodies (RBs) within a membrane‑bound inclusion. RBs are divided once more into elementary bodies 24 to 48 hours after infection and they are eventually released through lysis of the host cell. The chlamydial infection, like the gonococcal infection, is the possibility of severe sequelae in both the eye and the genital tract. Chlamydia trachomatis infects epithelial cells in the eye and genital tract. The early stage of infection can present with a mucopurulent discharge, but infections are often asymptomatic at this stage. In most infected women, the infection has a resolution, but in women with persistent or repeated infections, it can spread upwards from the endocervix to the fallopian tubes, leading to infertility or ectopic pregnancy because of tubal occlusion by scar tissue. It is a common etiologic agent in acute salpingitis, mainly in the adolescent’s population. With the exception of the lymphogranuloma venereum strains, which cause systemic illness and infect regional lymph nodes, Chlamydia trachomatis infection usually remains confined to mucosal surfaces, and it continues to produce enormous social and economic consequences despite advances in prevention, screening, and treatment.
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spelling doaj.art-ef80a86453b4432996b3b21b8dd94ab72023-01-28T01:04:53ZengZeppelini Editorial e ComunicacaoDST2177-82642022-08-01273-4Chlamydia trachomatis infections and their impact in the adolescent populationMartín Santalucía0Alicia Farinati1Universidad del SalvadorUniversidad del Salvador Chlamydia trachomatis is an obligate intracellular organism and can only replicate inside eukaryotic host cells. It has a unique developmental cycle, with metabolically inert, spore‑like elementary bodies that infect host cells and develop into metabolically active, replicative or reticulate bodies (RBs) within a membrane‑bound inclusion. RBs are divided once more into elementary bodies 24 to 48 hours after infection and they are eventually released through lysis of the host cell. The chlamydial infection, like the gonococcal infection, is the possibility of severe sequelae in both the eye and the genital tract. Chlamydia trachomatis infects epithelial cells in the eye and genital tract. The early stage of infection can present with a mucopurulent discharge, but infections are often asymptomatic at this stage. In most infected women, the infection has a resolution, but in women with persistent or repeated infections, it can spread upwards from the endocervix to the fallopian tubes, leading to infertility or ectopic pregnancy because of tubal occlusion by scar tissue. It is a common etiologic agent in acute salpingitis, mainly in the adolescent’s population. With the exception of the lymphogranuloma venereum strains, which cause systemic illness and infect regional lymph nodes, Chlamydia trachomatis infection usually remains confined to mucosal surfaces, and it continues to produce enormous social and economic consequences despite advances in prevention, screening, and treatment. https://bjstd.org/revista/article/view/733Chlamydia trachomatisadolescentbiologyimmunity
spellingShingle Martín Santalucía
Alicia Farinati
Chlamydia trachomatis infections and their impact in the adolescent population
DST
Chlamydia trachomatis
adolescent
biology
immunity
title Chlamydia trachomatis infections and their impact in the adolescent population
title_full Chlamydia trachomatis infections and their impact in the adolescent population
title_fullStr Chlamydia trachomatis infections and their impact in the adolescent population
title_full_unstemmed Chlamydia trachomatis infections and their impact in the adolescent population
title_short Chlamydia trachomatis infections and their impact in the adolescent population
title_sort chlamydia trachomatis infections and their impact in the adolescent population
topic Chlamydia trachomatis
adolescent
biology
immunity
url https://bjstd.org/revista/article/view/733
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AT aliciafarinati chlamydiatrachomatisinfectionsandtheirimpactintheadolescentpopulation