| Summary: | Electrode kinetics and study of ‘transition state’ with applied potential in case of
[M – antibiotics – cephalothin] system were reported at pH = 7.30 ± 0.01 at suitable supporting
electrolyte at 25.0 0 C. The M = Co or Ni and antibiotics were doxycycline, chlortetracycline,
oxytetracycline, tetracycline, minocycline, amoxicillin and chloramphenicol used as primary
ligands and cephalothin as secondary ligand. Kinetic parameters viz. transfer coefficient (a),
degree of irreversibility (l), diffusion coefficient (D) and rate constant (k) were determined.
The values of a and k varied from 0.41 to 0.59 and 2.60 X 10 -3 cm s -1 to 9.67 X 10 -3 cm s -1
in case of [Co – antibiotics – cephalothin] system. In case of [Ni – antibiotics – cephalothin],
a and k varied from 0.41 to 0.58 and 2.34 X 10 -3 cm s -1 to 9.19 X 10 -3 cm s -1 respectively
confirmed that transition state behaves between oxidant and reductant response to applied
potential and it adjusts it self in such a way that the same is located midway between dropping
mercury electrode and solution interface. The values of rate constant confirmed the
quasireversible nature of electrode processes. The stability constants (logb) of complexes
were also determined.
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