Soluble and Immobilized Anti-CD3/28 Distinctively Expand and Differentiate Primary Human T Cells: An Implication for Adoptive T Cell Therapy

Soluble and Immobilized Anti-CD3/28 Distinctively Expand and Differentiate Primary Human T Cells: An Implication for Adoptive T Cell Therapy

Cell-based cancer therapies have led to a paradigm shift in the treatment of patients with various cancers. To date, a vast majority of cancer immunotherapies have used genetically engineered T cells to target tumors. Stimulation and ex vivo expansion of T cells, as one of the crucial starting mate...

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Bibliographic Details
Main Authors: Tahereh Soltantoye, Behnia Akbari, Hamid Reza Mirzaei, Jamshid Hadjati
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2022-12-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Adoptive cellular therapy
Immobilized antibodies
Lymphocyte activation
Memory phenotype
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/3613

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