Xiaoxuming decoction cutting formula reduces LPS-stimulated inflammation in BV-2 cells by regulating miR-9-5p in microglia exosomes

Xiaoxuming decoction cutting formula reduces LPS-stimulated inflammation in BV-2 cells by regulating miR-9-5p in microglia exosomes

The Background: Stroke is one of the leading causes of morbidity and mortality, and the inflammatory mechanism plays a crucial role in stroke-related brain injury and post-ischemic tissue damage. Xiaoxuming decoction (XXMD) is the first prescription for the treatment of “zhongfeng” (a broad concept...

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Bibliographic Details
Main Authors: Menglei Wang, Yuting Yang, Yanlei Guo, Ruirong Tan, Yanmei Sheng, Huawei Chui, Ping Chen, Hua Luo, Zhujun Ying, Li Li, Jin Zeng, Junning Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
xiaoxuming decoction cutting formula
neuroinflammation
miR-9-5p
microglia exosomes
smallRNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1183612/full

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