Preliminary study of neuroimaging and psychophysiology in adults with ADHD

Attention Deficit Hyperactivity Disorder  (ADHD) affects in both children and adults leading to poor executive functioning and quality of life. However, very little study focuses on neuroimaging and psychophysiology in the adults with ADHD. This preliminary study aimed to report neuroimaging and ps...

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Main Authors: Ni Chun Hung, Shin-Hsien Lin, Mei Hung Chi, Po See Chen, I Hui Lee, Kao Chin Chen, Yen Kuang Yang
Format: Article
Language:English
Published: Rajanagarindra Institute of Child Development 2014-07-01
Series:International Journal of Child Development and Mental Health
Subjects:
Online Access:https://www.tci-thaijo.org/index.php/cdmh/article/view/66599
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author Ni Chun Hung
Shin-Hsien Lin
Mei Hung Chi
Po See Chen
I Hui Lee
Kao Chin Chen
Yen Kuang Yang
author_facet Ni Chun Hung
Shin-Hsien Lin
Mei Hung Chi
Po See Chen
I Hui Lee
Kao Chin Chen
Yen Kuang Yang
author_sort Ni Chun Hung
collection DOAJ
description Attention Deficit Hyperactivity Disorder  (ADHD) affects in both children and adults leading to poor executive functioning and quality of life. However, very little study focuses on neuroimaging and psychophysiology in the adults with ADHD. This preliminary study aimed to report neuroimaging and psychophysiology outcomes in the adults with ADHD. Participants in this study consisted of three groups: unaffected fathers of offspring with ADHD, adults with ADHD, and matched controls, were enrolled. A psychological battery was used in order to assess the participants’ cool cognitive function. Levels of dopaminergic activity were assessed by using the single positron emission computed tomography (SPECT) with [99mTc] TRODAT-1. In a pilot test for further study, the Iowa gambling test in a mock functional MRI was conducted. Molecular neuroimaging indicated the pivotal role of dopaminergicactivity altered a swellas functional brain imaging demonstrated difference between cool and hot executive functions. Using the Event-Related Potentials (ERP), the P300 amplitude of adults with ADHD was found to be lower than healthy group. In conclusions, Neuroimaging and psychophysiology outcome were effectively identified in adult with ADHD. Further study of neuroendocrinological factors might be related.
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spelling doaj.art-ef900902f52d463db0defb5f5d85acc22022-12-21T19:15:21ZengRajanagarindra Institute of Child DevelopmentInternational Journal of Child Development and Mental Health2286-74812586-887X2014-07-0122233566599Preliminary study of neuroimaging and psychophysiology in adults with ADHDNi Chun Hung0Shin-Hsien Lin1Mei Hung Chi2Po See Chen3I Hui Lee4Kao Chin Chen5Yen Kuang Yang6Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan Department of Psychiatry, Chi-Mei Foundation Medical Center, Tainan, TaiwanDepartment of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan.Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, NationalCheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, TaiwanDepartment of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, TaiwanDepartment of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan. Department of Psychiatry, National Cheng Kung University, Dou-Liou Branch, Yunlin, Taiwan.Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Addiction Research Center, National Cheng Kung University, Tainan, TaiwanAttention Deficit Hyperactivity Disorder  (ADHD) affects in both children and adults leading to poor executive functioning and quality of life. However, very little study focuses on neuroimaging and psychophysiology in the adults with ADHD. This preliminary study aimed to report neuroimaging and psychophysiology outcomes in the adults with ADHD. Participants in this study consisted of three groups: unaffected fathers of offspring with ADHD, adults with ADHD, and matched controls, were enrolled. A psychological battery was used in order to assess the participants’ cool cognitive function. Levels of dopaminergic activity were assessed by using the single positron emission computed tomography (SPECT) with [99mTc] TRODAT-1. In a pilot test for further study, the Iowa gambling test in a mock functional MRI was conducted. Molecular neuroimaging indicated the pivotal role of dopaminergicactivity altered a swellas functional brain imaging demonstrated difference between cool and hot executive functions. Using the Event-Related Potentials (ERP), the P300 amplitude of adults with ADHD was found to be lower than healthy group. In conclusions, Neuroimaging and psychophysiology outcome were effectively identified in adult with ADHD. Further study of neuroendocrinological factors might be related.https://www.tci-thaijo.org/index.php/cdmh/article/view/66599ADHDDopamineIowa gambling testneuroimagingP300 amplitude
spellingShingle Ni Chun Hung
Shin-Hsien Lin
Mei Hung Chi
Po See Chen
I Hui Lee
Kao Chin Chen
Yen Kuang Yang
Preliminary study of neuroimaging and psychophysiology in adults with ADHD
International Journal of Child Development and Mental Health
ADHD
Dopamine
Iowa gambling test
neuroimaging
P300 amplitude
title Preliminary study of neuroimaging and psychophysiology in adults with ADHD
title_full Preliminary study of neuroimaging and psychophysiology in adults with ADHD
title_fullStr Preliminary study of neuroimaging and psychophysiology in adults with ADHD
title_full_unstemmed Preliminary study of neuroimaging and psychophysiology in adults with ADHD
title_short Preliminary study of neuroimaging and psychophysiology in adults with ADHD
title_sort preliminary study of neuroimaging and psychophysiology in adults with adhd
topic ADHD
Dopamine
Iowa gambling test
neuroimaging
P300 amplitude
url https://www.tci-thaijo.org/index.php/cdmh/article/view/66599
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