Reinfection with SARS-CoV-2: An inconvenient truth?
Data show that antibody-related immunity against SARS-CoV-2 may not be long-lasting. We report two cases regarded as cured from COVID-19, which presented again with symptoms and a positive SARS-CoV-2 RT-PCR test. Case one, a 60-year-old male, had a biphasic presentation of symptoms compatible with C...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2022;volume=11;issue=1;spage=366;epage=369;aulast=Sonie |
| _version_ | 1828544227740483584 |
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| author | Pedro Sonie Jorge Manuel-Silva Alexandra Rafael Luis Amorim-Alves |
| author_facet | Pedro Sonie Jorge Manuel-Silva Alexandra Rafael Luis Amorim-Alves |
| author_sort | Pedro Sonie |
| collection | DOAJ |
| description | Data show that antibody-related immunity against SARS-CoV-2 may not be long-lasting. We report two cases regarded as cured from COVID-19, which presented again with symptoms and a positive SARS-CoV-2 RT-PCR test. Case one, a 60-year-old male, had a biphasic presentation of symptoms compatible with COVID-19 infection, associated with a positive RT-PCR test. Case two, a 25-year-old female, had a first positive RT-PCR test during hospital screening, and months later a symptomatic presentation of COVID-19, associated with a positive RT-PCR test. All cases were immunocompetent. Anti-IgG-SARS-CoV-2 blood samples were negative in both. Elevation of analytical inflammatory markers suggested new infection in both cases. COVID-19 reinfection may be a differential diagnosis and primary care physicians should acknowledge it. Previously cured patients should be encouraged to comply with health public preventive measures. |
| first_indexed | 2024-12-12T02:26:32Z |
| format | Article |
| id | doaj.art-ef929e08041e46ec84569e69ef1c723c |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-12-12T02:26:32Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-ef929e08041e46ec84569e69ef1c723c2022-12-22T00:41:32ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632022-01-0111136636910.4103/jfmpc.jfmpc_1490_21Reinfection with SARS-CoV-2: An inconvenient truth?Pedro SonieJorge Manuel-SilvaAlexandra RafaelLuis Amorim-AlvesData show that antibody-related immunity against SARS-CoV-2 may not be long-lasting. We report two cases regarded as cured from COVID-19, which presented again with symptoms and a positive SARS-CoV-2 RT-PCR test. Case one, a 60-year-old male, had a biphasic presentation of symptoms compatible with COVID-19 infection, associated with a positive RT-PCR test. Case two, a 25-year-old female, had a first positive RT-PCR test during hospital screening, and months later a symptomatic presentation of COVID-19, associated with a positive RT-PCR test. All cases were immunocompetent. Anti-IgG-SARS-CoV-2 blood samples were negative in both. Elevation of analytical inflammatory markers suggested new infection in both cases. COVID-19 reinfection may be a differential diagnosis and primary care physicians should acknowledge it. Previously cured patients should be encouraged to comply with health public preventive measures.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2022;volume=11;issue=1;spage=366;epage=369;aulast=Soniefamily medicineinfectious diseasespublic health |
| spellingShingle | Pedro Sonie Jorge Manuel-Silva Alexandra Rafael Luis Amorim-Alves Reinfection with SARS-CoV-2: An inconvenient truth? Journal of Family Medicine and Primary Care family medicine infectious diseases public health |
| title | Reinfection with SARS-CoV-2: An inconvenient truth? |
| title_full | Reinfection with SARS-CoV-2: An inconvenient truth? |
| title_fullStr | Reinfection with SARS-CoV-2: An inconvenient truth? |
| title_full_unstemmed | Reinfection with SARS-CoV-2: An inconvenient truth? |
| title_short | Reinfection with SARS-CoV-2: An inconvenient truth? |
| title_sort | reinfection with sars cov 2 an inconvenient truth |
| topic | family medicine infectious diseases public health |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2022;volume=11;issue=1;spage=366;epage=369;aulast=Sonie |
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