Eight New Peptaibols from Sponge-Associated Trichoderma atroviride
Eight new and four known peptaibols were isolated from a strain of the fungus, Trichoderma atroviride (NF16), which was cultured from an Axinellid sponge collected from the East Mediterranean coast of Israel. The structures of the pure compounds were determined using HRMS, MS/MS and one- and two-dim...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-12-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/11/12/4937 |
| _version_ | 1828372183889477632 |
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| author | Irina Panizel Oded Yarden Micha Ilan Shmuel Carmeli |
| author_facet | Irina Panizel Oded Yarden Micha Ilan Shmuel Carmeli |
| author_sort | Irina Panizel |
| collection | DOAJ |
| description | Eight new and four known peptaibols were isolated from a strain of the fungus, Trichoderma atroviride (NF16), which was cultured from an Axinellid sponge collected from the East Mediterranean coast of Israel. The structures of the pure compounds were determined using HRMS, MS/MS and one- and two-dimensional NMR measurements. The isolated compounds belong to the trichorzianines, a family of 19-residue linear hydrophobic peptides containing a high proportion of α-aminoisobutyric acid (Aib), an acetylated N-terminus and a C-terminal amino alcohol. These new peptaibols exhibited antimicrobial activity against environmental bacteria isolated from the Mediterranean coast of Israel. |
| first_indexed | 2024-04-14T07:00:47Z |
| format | Article |
| id | doaj.art-ef9456e81f874e6db4430f478deec316 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-14T07:00:47Z |
| publishDate | 2013-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-ef9456e81f874e6db4430f478deec3162022-12-22T02:06:47ZengMDPI AGMarine Drugs1660-33972013-12-0111124937496010.3390/md11124937md11124937Eight New Peptaibols from Sponge-Associated Trichoderma atrovirideIrina Panizel0Oded Yarden1Micha Ilan2Shmuel Carmeli3Raymond and Beverly Sackler School of Chemistry and Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, IsraelDepartment of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot 76100, IsraelDepartment of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, IsraelRaymond and Beverly Sackler School of Chemistry and Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, IsraelEight new and four known peptaibols were isolated from a strain of the fungus, Trichoderma atroviride (NF16), which was cultured from an Axinellid sponge collected from the East Mediterranean coast of Israel. The structures of the pure compounds were determined using HRMS, MS/MS and one- and two-dimensional NMR measurements. The isolated compounds belong to the trichorzianines, a family of 19-residue linear hydrophobic peptides containing a high proportion of α-aminoisobutyric acid (Aib), an acetylated N-terminus and a C-terminal amino alcohol. These new peptaibols exhibited antimicrobial activity against environmental bacteria isolated from the Mediterranean coast of Israel.http://www.mdpi.com/1660-3397/11/12/4937peptaibolstrichorzianinesTrichoderma atrovirideAxinella polypoidesAxinella verrucosa |
| spellingShingle | Irina Panizel Oded Yarden Micha Ilan Shmuel Carmeli Eight New Peptaibols from Sponge-Associated Trichoderma atroviride Marine Drugs peptaibols trichorzianines Trichoderma atroviride Axinella polypoides Axinella verrucosa |
| title | Eight New Peptaibols from Sponge-Associated Trichoderma atroviride |
| title_full | Eight New Peptaibols from Sponge-Associated Trichoderma atroviride |
| title_fullStr | Eight New Peptaibols from Sponge-Associated Trichoderma atroviride |
| title_full_unstemmed | Eight New Peptaibols from Sponge-Associated Trichoderma atroviride |
| title_short | Eight New Peptaibols from Sponge-Associated Trichoderma atroviride |
| title_sort | eight new peptaibols from sponge associated trichoderma atroviride |
| topic | peptaibols trichorzianines Trichoderma atroviride Axinella polypoides Axinella verrucosa |
| url | http://www.mdpi.com/1660-3397/11/12/4937 |
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