Identification of Novel Molecular Subgroups in Esophageal Adenocarcinoma to Predict Response to Neo-Adjuvant Therapies

Identification of Novel Molecular Subgroups in Esophageal Adenocarcinoma to Predict Response to Neo-Adjuvant Therapies

Esophageal adenocarcinoma (EAC) is a highly aggressive cancer and its response to chemo- and radiotherapy is unpredictable. EACs are highly heterogeneous at the molecular level. The aim of this study was to perform gene expression analysis of EACs to identify distinct molecular subgroups and to inve...

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Bibliographic Details
Main Authors: Sanne J. M. Hoefnagel, Willem J. Koemans, Hina N. Khan, Jan Koster, Sybren L. Meijer, Jolanda M. van Dieren, Liudmila L. Kodach, Johanna W. van Sandick, Silvia Calpe, Carmen M. del Sancho-Serra, Ana C. P. Correia, Mark I. Van Berge Henegouwen, Suzanne S. Gisbertz, Maarten C. C. M. Hulshof, Sandro Mattioli, Manon C. W. Spaander, Kausilia K. Krishnadath
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
esophageal adenocarcinoma
RNA sequencing
subgroups
predicting response to therapy
Online Access:https://www.mdpi.com/2072-6694/14/18/4498

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https://www.mdpi.com/2072-6694/14/18/4498

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