The analysis of the kinetics of extraction of resinoids and hypericines from the amber, Hypericum perforatum L

The kinetics of the extraction of the overall extracted materials (resinoids), total hypericine, hypericine and pseudohypericine from amber (Hypericum perforatum L) was investigated by the procedure of maceration both with and without ultra-sound, using methanol as the extractant. It was found that...

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Main Authors: Šmelcerović Andrija A., Đorđević Siniša M., Lepojević Žika D., Veličković Dragan T.
Format: Article
Language:English
Published: Serbian Chemical Society 2002-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2002/0352-51390206457S.pdf
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author Šmelcerović Andrija A.
Đorđević Siniša M.
Lepojević Žika D.
Veličković Dragan T.
author_facet Šmelcerović Andrija A.
Đorđević Siniša M.
Lepojević Žika D.
Veličković Dragan T.
author_sort Šmelcerović Andrija A.
collection DOAJ
description The kinetics of the extraction of the overall extracted materials (resinoids), total hypericine, hypericine and pseudohypericine from amber (Hypericum perforatum L) was investigated by the procedure of maceration both with and without ultra-sound, using methanol as the extractant. It was found that the period of fast extraction with intensification of the extraction of resinoid by ultra-sound was significantly shorter (about 20 minutes) than was needed for the extraction without ultra-sound (about 5 h). Similar results were also obtained for the extraction of the other tested substances. It can be concluded that better drug exploitation can be achieved in a much shorter extraction time by intensification of the extraction using ultra-sound. By preparation of herbal material through pulverization, a significant grade of herbal tissue structure disintegration was achieved, so that turbulent mass transfer plays a dominant role in the extraction. The results show that the coefficient values of fast extraction (b) are approximately the same for all the investigated kinetics.
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spelling doaj.art-ef9edd6b6f9b4593a4d91e75358891e42022-12-21T23:27:17ZengSerbian Chemical SocietyJournal of the Serbian Chemical Society0352-51391820-74212002-01-0167645746310.2298/JSC0206457S0352-51390206457SThe analysis of the kinetics of extraction of resinoids and hypericines from the amber, Hypericum perforatum LŠmelcerović Andrija A.0Đorđević Siniša M.1Lepojević Žika D.2Veličković Dragan T.3Chemical Industry 'Nevena', LeskovacFaculty of Technology, LeskovacFaculty of Technology, Novi SadPharmaceutical and Chemical Industry 'Zdravlje', LeskovacThe kinetics of the extraction of the overall extracted materials (resinoids), total hypericine, hypericine and pseudohypericine from amber (Hypericum perforatum L) was investigated by the procedure of maceration both with and without ultra-sound, using methanol as the extractant. It was found that the period of fast extraction with intensification of the extraction of resinoid by ultra-sound was significantly shorter (about 20 minutes) than was needed for the extraction without ultra-sound (about 5 h). Similar results were also obtained for the extraction of the other tested substances. It can be concluded that better drug exploitation can be achieved in a much shorter extraction time by intensification of the extraction using ultra-sound. By preparation of herbal material through pulverization, a significant grade of herbal tissue structure disintegration was achieved, so that turbulent mass transfer plays a dominant role in the extraction. The results show that the coefficient values of fast extraction (b) are approximately the same for all the investigated kinetics.http://www.doiserbia.nb.rs/img/doi/0352-5139/2002/0352-51390206457S.pdfhypericum perforatum l.kinetics of extractionresinoidstotal hypericinehypericinepseudohypericine.
spellingShingle Šmelcerović Andrija A.
Đorđević Siniša M.
Lepojević Žika D.
Veličković Dragan T.
The analysis of the kinetics of extraction of resinoids and hypericines from the amber, Hypericum perforatum L
Journal of the Serbian Chemical Society
hypericum perforatum l.
kinetics of extraction
resinoids
total hypericine
hypericine
pseudohypericine.
title The analysis of the kinetics of extraction of resinoids and hypericines from the amber, Hypericum perforatum L
title_full The analysis of the kinetics of extraction of resinoids and hypericines from the amber, Hypericum perforatum L
title_fullStr The analysis of the kinetics of extraction of resinoids and hypericines from the amber, Hypericum perforatum L
title_full_unstemmed The analysis of the kinetics of extraction of resinoids and hypericines from the amber, Hypericum perforatum L
title_short The analysis of the kinetics of extraction of resinoids and hypericines from the amber, Hypericum perforatum L
title_sort analysis of the kinetics of extraction of resinoids and hypericines from the amber hypericum perforatum l
topic hypericum perforatum l.
kinetics of extraction
resinoids
total hypericine
hypericine
pseudohypericine.
url http://www.doiserbia.nb.rs/img/doi/0352-5139/2002/0352-51390206457S.pdf
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