Hypoglycemia and associated comorbidities among newborns of mothers with diabetes in an academic tertiary care center
BackgroundHypoglycemia is considered the common metabolic problem in newborns with serious long-term sequelae. This study evaluates the incidence of hypoglycemia in the newborns of mothers with diabetes mellitus and assesses the comorbidities that affect the newborns of mothers with gestational diab...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-10-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2023.1267248/full |
| _version_ | 1797660683405361152 |
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| author | Maha Bamehrez |
| author_facet | Maha Bamehrez |
| author_sort | Maha Bamehrez |
| collection | DOAJ |
| description | BackgroundHypoglycemia is considered the common metabolic problem in newborns with serious long-term sequelae. This study evaluates the incidence of hypoglycemia in the newborns of mothers with diabetes mellitus and assesses the comorbidities that affect the newborns of mothers with gestational diabetes compared with the newborns of mothers with pregestational diabetes mellitus.MethodsThis retrospective cohort study was conducted between January-2018 and December-2020. All admissions to the hospital nursery of the newborns of diabetic mothers with diabetes mellitus were included.ResultsThe study comprised 1,036 mothers with diabetes, of the newborns of mothers with pregestational diabetes, 22% had hypoglycemia, and of mothers with gestational diabetes, 12%. Mothers with pregestational diabetes had a significantly higher risk of needing an emergency cesarean section (OR: 2.1, 95% CI: 1.3–3.4); and of having a baby who is large for its gestational age (OR: 9.5, 95% CI: 2.6–35.5), must be admitted to the NICU (OR: 2.9, 95% CI: 1.5–5.6), has respiratory distress syndrome (OR: 3.3, 95% CI: 1.5–7.4), and needs gavage feeding (OR: 3.5, 95% CI: 1.4–8.9).ConclusionAbout 13% of the newborns of mothers with diabetes had hypoglycemia. Significantly more of these newborns were of mothers with pregestational diabetes than of mothers with gestational diabetes. Newborn of mothers with pregestational diabetes mellitus have the risk of large weight and neurological problems, such as sucking difficulties, length of hospital stay, NICU admission, and respiratory distress syndrome. |
| first_indexed | 2024-03-11T18:34:26Z |
| format | Article |
| id | doaj.art-ef9f981deec440d1bf10be6cb558bd2e |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-03-11T18:34:26Z |
| publishDate | 2023-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-ef9f981deec440d1bf10be6cb558bd2e2023-10-13T07:10:38ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-10-011110.3389/fped.2023.12672481267248Hypoglycemia and associated comorbidities among newborns of mothers with diabetes in an academic tertiary care centerMaha BamehrezBackgroundHypoglycemia is considered the common metabolic problem in newborns with serious long-term sequelae. This study evaluates the incidence of hypoglycemia in the newborns of mothers with diabetes mellitus and assesses the comorbidities that affect the newborns of mothers with gestational diabetes compared with the newborns of mothers with pregestational diabetes mellitus.MethodsThis retrospective cohort study was conducted between January-2018 and December-2020. All admissions to the hospital nursery of the newborns of diabetic mothers with diabetes mellitus were included.ResultsThe study comprised 1,036 mothers with diabetes, of the newborns of mothers with pregestational diabetes, 22% had hypoglycemia, and of mothers with gestational diabetes, 12%. Mothers with pregestational diabetes had a significantly higher risk of needing an emergency cesarean section (OR: 2.1, 95% CI: 1.3–3.4); and of having a baby who is large for its gestational age (OR: 9.5, 95% CI: 2.6–35.5), must be admitted to the NICU (OR: 2.9, 95% CI: 1.5–5.6), has respiratory distress syndrome (OR: 3.3, 95% CI: 1.5–7.4), and needs gavage feeding (OR: 3.5, 95% CI: 1.4–8.9).ConclusionAbout 13% of the newborns of mothers with diabetes had hypoglycemia. Significantly more of these newborns were of mothers with pregestational diabetes than of mothers with gestational diabetes. Newborn of mothers with pregestational diabetes mellitus have the risk of large weight and neurological problems, such as sucking difficulties, length of hospital stay, NICU admission, and respiratory distress syndrome.https://www.frontiersin.org/articles/10.3389/fped.2023.1267248/fullhypoglycemianeonatalsepsisglucosnewbornmorbididty |
| spellingShingle | Maha Bamehrez Hypoglycemia and associated comorbidities among newborns of mothers with diabetes in an academic tertiary care center Frontiers in Pediatrics hypoglycemia neonatal sepsis glucos newborn morbididty |
| title | Hypoglycemia and associated comorbidities among newborns of mothers with diabetes in an academic tertiary care center |
| title_full | Hypoglycemia and associated comorbidities among newborns of mothers with diabetes in an academic tertiary care center |
| title_fullStr | Hypoglycemia and associated comorbidities among newborns of mothers with diabetes in an academic tertiary care center |
| title_full_unstemmed | Hypoglycemia and associated comorbidities among newborns of mothers with diabetes in an academic tertiary care center |
| title_short | Hypoglycemia and associated comorbidities among newborns of mothers with diabetes in an academic tertiary care center |
| title_sort | hypoglycemia and associated comorbidities among newborns of mothers with diabetes in an academic tertiary care center |
| topic | hypoglycemia neonatal sepsis glucos newborn morbididty |
| url | https://www.frontiersin.org/articles/10.3389/fped.2023.1267248/full |
| work_keys_str_mv | AT mahabamehrez hypoglycemiaandassociatedcomorbiditiesamongnewbornsofmotherswithdiabetesinanacademictertiarycarecenter |