Development of Aptamer-Based TID Assays Using Thermophoresis and Microarrays

Development of Aptamer-Based TID Assays Using Thermophoresis and Microarrays

Aptamers are single-stranded oligonucleotides which can be used as alternative recognition elements for protein detection, because aptamers bind their targets with a high affinity similar to antibodies. Due to the target-induced conformational changes of aptamers, these oligonucleotides can be appli...

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Bibliographic Details
Main Authors: Tracy Kurth, Sandra Witt, Svenja Bolten, Janice-Joy Waniek, Carlotta Kortmann, Antonina Lavrentieva, Thomas Scheper, Johanna-Gabriela Walter
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Biosensors
Subjects:
aptamer
microarray
protein detection
target-induced dissociation (tid)
biosensor
thermophoresis
vascular endothelial growth factor (vegf)
Online Access:https://www.mdpi.com/2079-6374/9/4/124

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