Summary: | Aim: To assess the role of DW-MRI and ADC value in evaluation of hepatic focal lesions in cirrhotic patients compared to triphasic CT and dynamic MRI.
Patients and methods: 164 cirrhotic patients with hepatic focal lesions were subjected to full clinical examination and laboratory evaluations. DW-MRI with ADC value measurement was done for all patients in addition to triphasic CT and dynamic MRI. The radiological diagnosis was correlated to pathological results in all patients.
Results: 164 included cirrhotic patients (312 lesions), their mean age (57.7 ± 3.2). 206 lesions were diagnosed pathologically as malignant; hepatocellular carcinoma was the most common (83%), metastasis (32%) and cholangiocarcinoma (1.5%). 106 lesions were diagnosed pathologically as benign; hemangioma was the most common (61.3%), cirrhotic regeneration nodules (32.1%) and cysts (6.6%). The mean ADC values for malignant lesions were lower than those for benign lesions with significant P-value (0.007) and cutoff value 1.2 × 10−3 mm2/sec. DWI-MRI was more accurate in the assessment of HFLs (96.1% sensitivity, 98.1% specificity and 96.8% accuracy) than triphasic CT and dynamic MRI.
Conclusion: DW-MRI with ADC value can be used in the assessment of HFLs in cirrhotic patients with comparable results to dynamic MRI and more accurate than the use of triphasic CT.
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