COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-Analysis

Mass vaccination against COVID-19 is necessary to control the pandemic. COVID-19 vaccines are now recommended during pregnancy to prevent the disease. A systematic review of the literature in the electronic databases PubMed and EMBASE was performed and we aimed to investigate the attitude of documen...

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Main Authors: Antigoni Sarantaki, Vasiliki Evangelia Kalogeropoulou, Chrysoula Taskou, Christina Nanou, Aikaterini Lykeridou
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/10/12/2055
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author Antigoni Sarantaki
Vasiliki Evangelia Kalogeropoulou
Chrysoula Taskou
Christina Nanou
Aikaterini Lykeridou
author_facet Antigoni Sarantaki
Vasiliki Evangelia Kalogeropoulou
Chrysoula Taskou
Christina Nanou
Aikaterini Lykeridou
author_sort Antigoni Sarantaki
collection DOAJ
description Mass vaccination against COVID-19 is necessary to control the pandemic. COVID-19 vaccines are now recommended during pregnancy to prevent the disease. A systematic review of the literature in the electronic databases PubMed and EMBASE was performed and we aimed to investigate the attitude of documents towards COVID-19 vaccination and the prognostic factors of vaccination hesitation. A meta-analysis was also conducted to estimate the overall percentage of pregnant women who were willing to be vaccinated or had been vaccinated against COVID-19. A total of 18 studies were included in the review and meta-analysis. The acceptance rate of vaccination against COVID-19 among pregnant women ranged from 17.6% to 84.5%. The pooled proportion of acceptance of vaccination against COVID-19 in pregnant women was 0.53 (95% CI: 0.44–0.61). Predictors of acceptance of COVID-19 vaccination were older age, White race, occupational status, higher level of education, comorbidities, third trimester of pregnancy, influenza vaccination, knowledge about COVID-19, and confidence that vaccines for COVID-19 are safe and effective. The prevalence of COVID-19 vaccination in pregnant women is low. Targeted information campaigns are needed to increase vaccine education in this population.
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spelling doaj.art-efa617c874ec4cf086fa757859c251f22023-11-24T18:31:54ZengMDPI AGVaccines2076-393X2022-11-011012205510.3390/vaccines10122055COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-AnalysisAntigoni Sarantaki0Vasiliki Evangelia Kalogeropoulou1Chrysoula Taskou2Christina Nanou3Aikaterini Lykeridou4Midwifery Department, University of West Attica, 12243 Athens, GreeceFree-Lancer Midwife, 15123 Athens, GreeceAlexandra Maternity Hospital, 11528 Athens, GreeceMidwifery Department, University of West Attica, 12243 Athens, GreeceMidwifery Department, University of West Attica, 12243 Athens, GreeceMass vaccination against COVID-19 is necessary to control the pandemic. COVID-19 vaccines are now recommended during pregnancy to prevent the disease. A systematic review of the literature in the electronic databases PubMed and EMBASE was performed and we aimed to investigate the attitude of documents towards COVID-19 vaccination and the prognostic factors of vaccination hesitation. A meta-analysis was also conducted to estimate the overall percentage of pregnant women who were willing to be vaccinated or had been vaccinated against COVID-19. A total of 18 studies were included in the review and meta-analysis. The acceptance rate of vaccination against COVID-19 among pregnant women ranged from 17.6% to 84.5%. The pooled proportion of acceptance of vaccination against COVID-19 in pregnant women was 0.53 (95% CI: 0.44–0.61). Predictors of acceptance of COVID-19 vaccination were older age, White race, occupational status, higher level of education, comorbidities, third trimester of pregnancy, influenza vaccination, knowledge about COVID-19, and confidence that vaccines for COVID-19 are safe and effective. The prevalence of COVID-19 vaccination in pregnant women is low. Targeted information campaigns are needed to increase vaccine education in this population.https://www.mdpi.com/2076-393X/10/12/2055COVID-19vaccinationhesitancy determinantspregnant women
spellingShingle Antigoni Sarantaki
Vasiliki Evangelia Kalogeropoulou
Chrysoula Taskou
Christina Nanou
Aikaterini Lykeridou
COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-Analysis
Vaccines
COVID-19
vaccination
hesitancy determinants
pregnant women
title COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-Analysis
title_full COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-Analysis
title_fullStr COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-Analysis
title_full_unstemmed COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-Analysis
title_short COVID-19 Vaccination and Related Determinants of Hesitancy among Pregnant Women: A Systematic Review and Meta-Analysis
title_sort covid 19 vaccination and related determinants of hesitancy among pregnant women a systematic review and meta analysis
topic COVID-19
vaccination
hesitancy determinants
pregnant women
url https://www.mdpi.com/2076-393X/10/12/2055
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