Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review
Zein, a protein extracted from maize, can be employed to easily produce nanoscale particles suitable for use as carrier systems. This review investigates the main methods for obtaining zein nanoparticles, as well as the problems and options available in the development of stable colloidal suspension...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2018-01-01
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| Series: | Frontiers in Chemistry |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fchem.2018.00006/full |
| _version_ | 1811211503536177152 |
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| author | Mônica Pascoli Renata de Lima Leonardo F. Fraceto |
| author_facet | Mônica Pascoli Renata de Lima Leonardo F. Fraceto |
| author_sort | Mônica Pascoli |
| collection | DOAJ |
| description | Zein, a protein extracted from maize, can be employed to easily produce nanoscale particles suitable for use as carrier systems. This review investigates the main methods for obtaining zein nanoparticles, as well as the problems and options available in the development of stable colloidal suspensions. Considerable gaps were identified in the literature concerning this topic, with studies being unclear about the factors that affect the stability of zein particles. In the vast majority of cases, no data are presented in relation to the stability of the formulations over time. It could be concluded that in order to produce a high quality system, detailed evaluation is required, considering factors including the zein concentration, pH, ionic strength, thermal treatment of the protein prior to preparation of the nanoparticles, strategies employing other materials as coatings, and the storage conditions. It is extremely important that these aspects should be considered during product development, prior to commercial-scale manufacture. |
| first_indexed | 2024-04-12T05:14:18Z |
| format | Article |
| id | doaj.art-efa63732d22b4729acb48ef163baa523 |
| institution | Directory Open Access Journal |
| issn | 2296-2646 |
| language | English |
| last_indexed | 2024-04-12T05:14:18Z |
| publishDate | 2018-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Chemistry |
| spelling | doaj.art-efa63732d22b4729acb48ef163baa5232022-12-22T03:46:40ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462018-01-01610.3389/fchem.2018.00006303239Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-ReviewMônica Pascoli0Renata de Lima1Leonardo F. Fraceto2Environmental Chemistry, Institute of Science and Technology, São Paulo State University (UNESP), Sorocaba, BrazilDepartment of Biotechnology, University of Sorocaba, Sorocaba, BrazilEnvironmental Chemistry, Institute of Science and Technology, São Paulo State University (UNESP), Sorocaba, BrazilZein, a protein extracted from maize, can be employed to easily produce nanoscale particles suitable for use as carrier systems. This review investigates the main methods for obtaining zein nanoparticles, as well as the problems and options available in the development of stable colloidal suspensions. Considerable gaps were identified in the literature concerning this topic, with studies being unclear about the factors that affect the stability of zein particles. In the vast majority of cases, no data are presented in relation to the stability of the formulations over time. It could be concluded that in order to produce a high quality system, detailed evaluation is required, considering factors including the zein concentration, pH, ionic strength, thermal treatment of the protein prior to preparation of the nanoparticles, strategies employing other materials as coatings, and the storage conditions. It is extremely important that these aspects should be considered during product development, prior to commercial-scale manufacture.http://journal.frontiersin.org/article/10.3389/fchem.2018.00006/fullcolloidal stabilitythermal treatmentionic strengthzeinnanoparticles |
| spellingShingle | Mônica Pascoli Renata de Lima Leonardo F. Fraceto Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review Frontiers in Chemistry colloidal stability thermal treatment ionic strength zein nanoparticles |
| title | Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review |
| title_full | Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review |
| title_fullStr | Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review |
| title_full_unstemmed | Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review |
| title_short | Zein Nanoparticles and Strategies to Improve Colloidal Stability: A Mini-Review |
| title_sort | zein nanoparticles and strategies to improve colloidal stability a mini review |
| topic | colloidal stability thermal treatment ionic strength zein nanoparticles |
| url | http://journal.frontiersin.org/article/10.3389/fchem.2018.00006/full |
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