A novel sleep aid device to reduce sleep latency using air–CO2 mixed gas

IntroductionSleep is an indispensable component of human life. However, in modern times, the number of people suffering from sleep disorders, such as insomnia and sleep deprivation, has increased significantly. Therefore, to alleviate the discomfort to the patient due to lack of sleep, sleeping pill...

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Main Authors: Hyewon Han, Dongsin Kim, Jin Seok Kim, Lee Ku Kwac, Janghun Hyeon, Junhyoung Oh
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1163904/full
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author Hyewon Han
Dongsin Kim
Jin Seok Kim
Lee Ku Kwac
Janghun Hyeon
Junhyoung Oh
author_facet Hyewon Han
Dongsin Kim
Jin Seok Kim
Lee Ku Kwac
Janghun Hyeon
Junhyoung Oh
author_sort Hyewon Han
collection DOAJ
description IntroductionSleep is an indispensable component of human life. However, in modern times, the number of people suffering from sleep disorders, such as insomnia and sleep deprivation, has increased significantly. Therefore, to alleviate the discomfort to the patient due to lack of sleep, sleeping pills and various sleep aids are being introduced and used. However, sleeping drugs are prescribed only to a limited extent due to the side effects posed by them and resistance to such drugs developed by patients in the long term, and the majority of sleep aids are scientifically groundless products. This study aimed to develop a device that induced sleep by spraying a mixed gas of carbon dioxide and air to create an environment that could induce sleep, similar to the inside of a sealed vehicle, to control oxygen saturation in the body.MethodsBased on the stipulated safety standards and the human tidal volume, the target concentration of carbon dioxide was determined to be of three types: 15,000, 20,000, and 25,000 ppm. After analyzing diverse structures for safely mixing gases, the most appropriate shape, the reserve tank, was selected as the best suited structure. Various variables, such as spraying angle and distance, flow rate, atmospheric temperature, and nozzle length, were comprehensively measured and tested. Furthermore based on this aspect, diffusion simulation of carbon dioxide concentration and actual experiments were conducted. To secure the stability and reliability of the developed product, an accredited test was performed to investigate the error rate of carbon dioxide concentration. Furthermore, clinical trials comprising polysomnography and questionnaires confirmed the effectiveness of the developed product not only in reducing sleep latency but also in enhancing the overall sleep quality.ResultsWhen the developed device was put to use in reality, sleep latency was decreased by 29.01%, on average, for those with a sleep latency of 5 min or more, compared to when the device was not in use. Moreover, the total sleep time was increased by 29.19 min, WASO was decreased by 13.17%, and sleep efficiency was increased by 5.48%. We also affirmed that the ODI and 90% ODI did not decrease when the device was used. Although different questions may be raised about the safety of using a gas such as carbon dioxide (CO2), the result that tODI was not reduced shows that sleep aids using CO2 mixtures do not adversely affect human health.DiscussionThe results of this study suggest a new method that can be used to treat sleep disorders including insomnia.
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spelling doaj.art-efa6aaa5e19840f68fe0bfe692b8f2862023-05-12T06:38:05ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-05-011410.3389/fneur.2023.11639041163904A novel sleep aid device to reduce sleep latency using air–CO2 mixed gasHyewon Han0Dongsin Kim1Jin Seok Kim2Lee Ku Kwac3Janghun Hyeon4Junhyoung Oh5Department of Computer Engineering, Hongik University, Seoul, Republic of KoreaNYX Inc., Hanam, Republic of KoreaNYX Inc., Hanam, Republic of KoreaDepartment of Carbon Convergence Engineering, Jeonju University, Jeonju, Republic of KoreaSemiconductor Research Institute, Korea University, Seoul, Republic of KoreaInstitute for Business Research and Education, Korea University, Seoul, Republic of KoreaIntroductionSleep is an indispensable component of human life. However, in modern times, the number of people suffering from sleep disorders, such as insomnia and sleep deprivation, has increased significantly. Therefore, to alleviate the discomfort to the patient due to lack of sleep, sleeping pills and various sleep aids are being introduced and used. However, sleeping drugs are prescribed only to a limited extent due to the side effects posed by them and resistance to such drugs developed by patients in the long term, and the majority of sleep aids are scientifically groundless products. This study aimed to develop a device that induced sleep by spraying a mixed gas of carbon dioxide and air to create an environment that could induce sleep, similar to the inside of a sealed vehicle, to control oxygen saturation in the body.MethodsBased on the stipulated safety standards and the human tidal volume, the target concentration of carbon dioxide was determined to be of three types: 15,000, 20,000, and 25,000 ppm. After analyzing diverse structures for safely mixing gases, the most appropriate shape, the reserve tank, was selected as the best suited structure. Various variables, such as spraying angle and distance, flow rate, atmospheric temperature, and nozzle length, were comprehensively measured and tested. Furthermore based on this aspect, diffusion simulation of carbon dioxide concentration and actual experiments were conducted. To secure the stability and reliability of the developed product, an accredited test was performed to investigate the error rate of carbon dioxide concentration. Furthermore, clinical trials comprising polysomnography and questionnaires confirmed the effectiveness of the developed product not only in reducing sleep latency but also in enhancing the overall sleep quality.ResultsWhen the developed device was put to use in reality, sleep latency was decreased by 29.01%, on average, for those with a sleep latency of 5 min or more, compared to when the device was not in use. Moreover, the total sleep time was increased by 29.19 min, WASO was decreased by 13.17%, and sleep efficiency was increased by 5.48%. We also affirmed that the ODI and 90% ODI did not decrease when the device was used. Although different questions may be raised about the safety of using a gas such as carbon dioxide (CO2), the result that tODI was not reduced shows that sleep aids using CO2 mixtures do not adversely affect human health.DiscussionThe results of this study suggest a new method that can be used to treat sleep disorders including insomnia.https://www.frontiersin.org/articles/10.3389/fneur.2023.1163904/fullsleep-inducingsleep latencysleep disordersleep qualitysleep aid device
spellingShingle Hyewon Han
Dongsin Kim
Jin Seok Kim
Lee Ku Kwac
Janghun Hyeon
Junhyoung Oh
A novel sleep aid device to reduce sleep latency using air–CO2 mixed gas
Frontiers in Neurology
sleep-inducing
sleep latency
sleep disorder
sleep quality
sleep aid device
title A novel sleep aid device to reduce sleep latency using air–CO2 mixed gas
title_full A novel sleep aid device to reduce sleep latency using air–CO2 mixed gas
title_fullStr A novel sleep aid device to reduce sleep latency using air–CO2 mixed gas
title_full_unstemmed A novel sleep aid device to reduce sleep latency using air–CO2 mixed gas
title_short A novel sleep aid device to reduce sleep latency using air–CO2 mixed gas
title_sort novel sleep aid device to reduce sleep latency using air co2 mixed gas
topic sleep-inducing
sleep latency
sleep disorder
sleep quality
sleep aid device
url https://www.frontiersin.org/articles/10.3389/fneur.2023.1163904/full
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