Conditioned Media from Head and Neck Cancer Cell Lines and Serum Samples from Head and Neck Cancer Patients Drive Catabolic Pathways in Cultured Muscle Cells

Conditioned Media from Head and Neck Cancer Cell Lines and Serum Samples from Head and Neck Cancer Patients Drive Catabolic Pathways in Cultured Muscle Cells

Background: The role of secreted factors from the tumor cells in driving cancer cachexia and especially muscle loss is unknown. We wanted to study both the action of secreted factors from head and neck cancer (HNC) cell lines and circulating factors in HNC patients on skeletal muscle protein catabol...

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Bibliographic Details
Main Authors: Nicolas Saroul, Nicolas Tardif, Bruno Pereira, Alexis Dissard, Laura Montrieul, Phelipe Sanchez, Jérôme Salles, Jens Erik Petersen, Towe Jakobson, Laurent Gilain, Thierry Mom, Yves Boirie, Olav Rooyakers, Stéphane Walrand
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Cancers
Subjects:
head and neck cancer
conditioned media
muscle cells protein metabolism
patient serum
Online Access:https://www.mdpi.com/2072-6694/15/6/1843

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