The Th17/Treg Cell Balance: A Gut Microbiota-Modulated Story
The intestinal tract of vertebrates is normally colonized with a remarkable number of commensal microorganisms that are collectively referred to as gut microbiota. Gut microbiota has been demonstrated to interact with immune cells and to modulate specific signaling pathways involving both innate and...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-11-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/7/12/583 |
| _version_ | 1819112220171173888 |
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| author | Hongyu Cheng Xiong Guan Dekun Chen Wentao Ma |
| author_facet | Hongyu Cheng Xiong Guan Dekun Chen Wentao Ma |
| author_sort | Hongyu Cheng |
| collection | DOAJ |
| description | The intestinal tract of vertebrates is normally colonized with a remarkable number of commensal microorganisms that are collectively referred to as gut microbiota. Gut microbiota has been demonstrated to interact with immune cells and to modulate specific signaling pathways involving both innate and adaptive immune processes. Accumulated evidence suggests that the imbalance of Th17 and Treg cells is associated with the development of many diseases. Herein, we emphatically present recent findings to show how specific gut microbiota organisms and metabolites shape the balance of Th17 and Treg cells. We also discuss the therapeutic potential of fecal microbiota transplantation (FMT) in diseases caused by the imbalance of Th17 and Treg cells |
| first_indexed | 2024-12-22T04:10:03Z |
| format | Article |
| id | doaj.art-efa8969daead404090a152cfb1a3d88b |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-12-22T04:10:03Z |
| publishDate | 2019-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-efa8969daead404090a152cfb1a3d88b2022-12-21T18:39:32ZengMDPI AGMicroorganisms2076-26072019-11-0171258310.3390/microorganisms7120583microorganisms7120583The Th17/Treg Cell Balance: A Gut Microbiota-Modulated StoryHongyu Cheng0Xiong Guan1Dekun Chen2Wentao Ma3Veterinary Immunology Laboratory, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling 712100, ChinaVeterinary Immunology Laboratory, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling 712100, ChinaVeterinary Immunology Laboratory, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling 712100, ChinaVeterinary Immunology Laboratory, College of Veterinary Medicine, Northwest Agriculture and Forestry University, Yangling 712100, ChinaThe intestinal tract of vertebrates is normally colonized with a remarkable number of commensal microorganisms that are collectively referred to as gut microbiota. Gut microbiota has been demonstrated to interact with immune cells and to modulate specific signaling pathways involving both innate and adaptive immune processes. Accumulated evidence suggests that the imbalance of Th17 and Treg cells is associated with the development of many diseases. Herein, we emphatically present recent findings to show how specific gut microbiota organisms and metabolites shape the balance of Th17 and Treg cells. We also discuss the therapeutic potential of fecal microbiota transplantation (FMT) in diseases caused by the imbalance of Th17 and Treg cellshttps://www.mdpi.com/2076-2607/7/12/583gut microbiotath17tregbalancemetabolites |
| spellingShingle | Hongyu Cheng Xiong Guan Dekun Chen Wentao Ma The Th17/Treg Cell Balance: A Gut Microbiota-Modulated Story Microorganisms gut microbiota th17 treg balance metabolites |
| title | The Th17/Treg Cell Balance: A Gut Microbiota-Modulated Story |
| title_full | The Th17/Treg Cell Balance: A Gut Microbiota-Modulated Story |
| title_fullStr | The Th17/Treg Cell Balance: A Gut Microbiota-Modulated Story |
| title_full_unstemmed | The Th17/Treg Cell Balance: A Gut Microbiota-Modulated Story |
| title_short | The Th17/Treg Cell Balance: A Gut Microbiota-Modulated Story |
| title_sort | th17 treg cell balance a gut microbiota modulated story |
| topic | gut microbiota th17 treg balance metabolites |
| url | https://www.mdpi.com/2076-2607/7/12/583 |
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