Plasmonic gold nanoagents for cancer imaging and therapy

Abstract Gold nanoparticles (AuNPs) are a popular material in the field of nanoscience because of their excellent biocompatibility and unique physical and chemical properties, and have been widely used in the biomedical field. AuNPs have a simple preparation method, controllable shape and size, high...

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Main Authors: Qinrui Fu, Xuan Zhang, Jibin Song, Huanghao Yang
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:View
Subjects:
Online Access:https://doi.org/10.1002/VIW.20200149
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author Qinrui Fu
Xuan Zhang
Jibin Song
Huanghao Yang
author_facet Qinrui Fu
Xuan Zhang
Jibin Song
Huanghao Yang
author_sort Qinrui Fu
collection DOAJ
description Abstract Gold nanoparticles (AuNPs) are a popular material in the field of nanoscience because of their excellent biocompatibility and unique physical and chemical properties, and have been widely used in the biomedical field. AuNPs have a simple preparation method, controllable shape and size, high electron density and atomic number, superparamagnetic properties, and radiation sensitization effect, and their optical absorbance can be adjusted to the required biological window; thus, AuNPs are suitable for cancer imaging (photoacoustic imaging, computed tomography, and magnetic resonance imaging), photothermal therapy, and radiotherapy. AuNPs can also be used as carriers to load photosensitizers or chemotherapeutic agents, and therefore, can also be used in photodynamic therapy and chemotherapy. In summary, AuNPs and their assemblies can simultaneously realize cancer diagnosis and treatment, providing a new idea in the development of precision medical treatment.
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spelling doaj.art-efa8c91d95594bd29ecc55f5832bc8a92022-12-21T20:45:44ZengWileyView2688-39882688-268X2021-10-0125n/an/a10.1002/VIW.20200149Plasmonic gold nanoagents for cancer imaging and therapyQinrui Fu0Xuan Zhang1Jibin Song2Huanghao Yang3MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry Fuzhou University Fuzhou ChinaMOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry Fuzhou University Fuzhou ChinaMOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry Fuzhou University Fuzhou ChinaMOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry Fuzhou University Fuzhou ChinaAbstract Gold nanoparticles (AuNPs) are a popular material in the field of nanoscience because of their excellent biocompatibility and unique physical and chemical properties, and have been widely used in the biomedical field. AuNPs have a simple preparation method, controllable shape and size, high electron density and atomic number, superparamagnetic properties, and radiation sensitization effect, and their optical absorbance can be adjusted to the required biological window; thus, AuNPs are suitable for cancer imaging (photoacoustic imaging, computed tomography, and magnetic resonance imaging), photothermal therapy, and radiotherapy. AuNPs can also be used as carriers to load photosensitizers or chemotherapeutic agents, and therefore, can also be used in photodynamic therapy and chemotherapy. In summary, AuNPs and their assemblies can simultaneously realize cancer diagnosis and treatment, providing a new idea in the development of precision medical treatment.https://doi.org/10.1002/VIW.20200149gold nanoparticlesimagingself‐assemblytheranosticstherapy
spellingShingle Qinrui Fu
Xuan Zhang
Jibin Song
Huanghao Yang
Plasmonic gold nanoagents for cancer imaging and therapy
View
gold nanoparticles
imaging
self‐assembly
theranostics
therapy
title Plasmonic gold nanoagents for cancer imaging and therapy
title_full Plasmonic gold nanoagents for cancer imaging and therapy
title_fullStr Plasmonic gold nanoagents for cancer imaging and therapy
title_full_unstemmed Plasmonic gold nanoagents for cancer imaging and therapy
title_short Plasmonic gold nanoagents for cancer imaging and therapy
title_sort plasmonic gold nanoagents for cancer imaging and therapy
topic gold nanoparticles
imaging
self‐assembly
theranostics
therapy
url https://doi.org/10.1002/VIW.20200149
work_keys_str_mv AT qinruifu plasmonicgoldnanoagentsforcancerimagingandtherapy
AT xuanzhang plasmonicgoldnanoagentsforcancerimagingandtherapy
AT jibinsong plasmonicgoldnanoagentsforcancerimagingandtherapy
AT huanghaoyang plasmonicgoldnanoagentsforcancerimagingandtherapy